Protein Alignment Septin2 and SHS1

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_010056.1
• Gene: SHS1 / 851373
• SGDID: S000002384
• Length: 551
• Species: Saccharomyces cerevisiae
• Alignment Length: 501
• Identity: 124/501 - (24%)
• Similarity: 216/501 - (43%)
• Gaps: 133/501 - (26%)

  Fly    36 KSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSF--------ESTPSPHTLPSVKLKAHT------ 86
            |..:.|..:.::..|..|.||:...:.|..|..        :|..|..:.|.||:.|.|
Yeast    16 KEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFN 80

  Fly    87 -----------YELQESNVRLKLTIC--------------------DTV--------GYGDQINK 112
                       ::...:|:...:||.                    |||        |.|:  |.
Yeast    81 SKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGE--NL 143

  Fly   113 DDSF--KAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLD 175
            |||.  :.|:.|::.||:..|.||.:|||: ....|:|:|:.||||.||||||:.:|:..||.:.
Yeast   144 DDSLCSEEVMSYLEQQFDIVLAEETRIKRN-PRFEDTRVHVALYFIEPTGHGLREVDVELMKSIS 207

  Fly   176 SKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQF---PTDDETVA-ETNTSMNSHIPF 236
            ...|::|:|.:||:.:|.||.:|:..|:.::....|.||:|   |.||:..: |.|.::.|..||
Yeast   208 KYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPF 272

  Fly   237 AVVGSTEFIKVGNKLIRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQ 301
            |::.|......|..:   |:||||.:.::::...|...|:.:|..:::::.::.|....||.||.
Yeast   273 AIITSDTRDSEGRYV---REYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRS 334

  Fly   302 KRL------EQMG---------------FSDV------------------DSDNKPIS--FQQT- 324
            ::|      |::|               |:.:                  |:....:|  |::.
Yeast   335 EKLSSVANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENE 399

  Fly   325 FEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKF-------EKLKRDHAEE--- 379
            :|....:..||.:.:...|||:..:..:|.|..::..:.:...||       |:.|..:..|
Yeast   400 YEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVP 464

  Fly   380 -----------KRKLEESRKALE-EDYLDFQRRKQQLATAHHTLTL 413
                       ::||||    || :...:.|:|.|:|....|.|.|
Yeast   465 YVLRHERILARQQKLEE----LEAQSAKELQKRIQELERKAHELKL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	92/332 (28%)
		PTZ00121	<285..393	CDD:173412	31/171 (18%)
SHS1	NP_010056.1	CDC3	1..519	CDD:227352	124/501 (25%)