Protein Alignment Septin2 and SEPTIN3

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001350774.1
• Gene: SEPTIN3 / 55964
• HGNCID: 10750
• Length: 856
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 128/295 - (43%)
• Similarity: 191/295 - (64%)
• Gaps: 9/295 - (3%)

  Fly    22 GHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFESTPS----PHTLP-SVK 81
            |::|.|::.:|:..|:::.||.||:|.:|::|||||||::|||.:......|    ...:| :|:
Human   538 GYIGIDTIIEQMRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVE 602

  Fly    82 LKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHD 146
            :||..:.::|..|::|||:.||.|:|||||.::.::.:..||:.|:|.:|:||:.|.|. ....|
Human   603 IKAIGHVIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQYEKFLKEEVNIARK-KRIPD 666

  Fly   147 SRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGV 211
            :|:|.|||||.||||.|:.|||..||.|...||||||||||||::..|...||.::.:||..||:
Human   667 TRVHCCLYFISPTGHSLRPLDLEFMKHLSKVVNIIPVIAKADTMTLEEKSEFKQRVRKELEVNGI 731

  Fly   212 HIY---QFPTDDETVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYPWGTVQVENETHCDFV 273
            ..|   :|..|.|...|.:......:|||||||.:..:|..|.:..|:.|||.::|||..||:|.
Human   732 EFYPQKEFDEDLEDKTENDKIRQESMPFAVVGSDKEYQVNGKRVLGRKTPWGIIEVENLNHCEFA 796

  Fly   274 KLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMG 308
            .||:.:|||:::|::|.||..|||.||.|||...|
Human   797 LLRDFVIRTHLQDLKEVTHNIHYETYRAKRLNDNG 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	122/275 (44%)
		PTZ00121	<285..393	CDD:173412	13/24 (54%)
SEPTIN3	NP_001350774.1	CDC_Septin	557..831	CDD:206649	122/274 (45%)