Protein Alignment Septin2 and SEPTIN2

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: XP_024308688.1
• Gene: SEPTIN2 / 4735
• HGNCID: 7729
• Length: 428
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 150/365 - (41%)
• Similarity: 217/365 - (59%)
• Gaps: 35/365 - (9%)

  Fly     7 FVDKKEVHLRTLKQS----------GHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMD 61
            |..:.|...:..||.          |:|||.:||:|:..|||:.||.|.:|.:||:|||||||::
Human    58 FGSRDEASQKMSKQQPTQFINPETPGYVGFANLPNQVHRKSVKKGFEFTLMVVGESGLGKSTLIN 122

  Fly    62 TLFNTSFESTPSPHTLP--------SVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKA 118
            :||.|...   ....:|        :|:::|.|.|::|..|:|:||:.||.||||.||..|.||.
Human   123 SLFLTDLY---PERVIPGAAEKIERTVQIEASTVEIEERGVKLRLTVVDTPGYGDAINCRDCFKT 184

  Fly   119 VVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPV 183
            ::.|||.|||.||.:|..:.|..:.  |:|:|.|.|||.|.|||||.||:..||.:.:||||:||
Human   185 IISYIDEQFERYLHDESGLNRRHII--DNRVHCCFYFISPFGHGLKPLDVAFMKAIHNKVNIVPV 247

  Fly   184 IAKADTISKVELQRFKAKIIQELNANGVHIYQFP----TDDETVAETNTSMNSHIPFAVVGSTEF 244
            ||||||::..|.:|.|.:|:.|:..:.:.||..|    .:||...|....:.:.|||:||||.:.
Human   248 IAKADTLTLKERERLKKRILDEIEEHNIKIYHLPDAESDEDEDFKEQTRLLKASIPFSVVGSNQL 312

  Fly   245 IKVGNKLIRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGF 309
            |:...|.:|.|.||||.|:|||..|.||:|||.||| |:|:|::|.|...|||.:|.:||::.|.
Human   313 IEAKGKKVRGRLYPWGVVEVENPEHNDFLKLRTMLI-THMQDLQEVTQDLHYENFRSERLKRGGR 376

  Fly   310 SDVDSDNKPISFQQTFEAKRSNHLAELQSKEEEVRQMFVQ 349
            .   .:|:.::..|....|.    |||:..:|.:.:|..|
Human   377 K---VENEDMNKDQILLEKE----AELRRMQEMIARMQAQ 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	126/279 (45%)
		PTZ00121	<285..393	CDD:173412	19/65 (29%)
SEPTIN2	XP_024308688.1	Septin	102..373	CDD:395596	126/276 (46%)