Protein Alignment Septin2 and septin8a

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_001108589.1
• Gene: septin8a / 321590
• ZFINID: ZDB-GENE-030131-309
• Length: 420
• Species: Danio rerio
• Alignment Length: 418
• Identity: 284/418 - (67%)
• Similarity: 334/418 - (79%)
• Gaps: 6/418 - (1%)

  Fly     2 SVEVDFVDKKEVHLRTLKQSGHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNT 66
            :.:||....:|  .|.|...|||||||||||||:|||..||.||::|:||||:||||||:|||||
Zfish     3 ATDVDIFSNEE--KRNLSLGGHVGFDSLPDQLVSKSVTQGFCFNILCVGETGIGKSTLMNTLFNT 65

  Fly    67 SFESTPSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYL 131
            .||:..:.|....|.|:..||:||||||.|||||.||||:||||||::|:|.:|||||.||||||
Zfish    66 MFENEEASHYQNGVYLRPRTYDLQESNVHLKLTIVDTVGFGDQINKEESYKPIVDYIDTQFENYL 130

  Fly   132 QEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQ 196
            |||||:||||...||:|||||||||.||||.|||||||.||||||||||||:|||||||||.||.
Zfish   131 QEELKVKRSLFNYHDTRIHICLYFISPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTISKSELH 195

  Fly   197 RFKAKIIQELNANGVHIYQFPTDDETVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYPWGT 261
            :||.||:.||.:|||.|||||||||.|.|.|:|||:|:|||||||.|.:|||||.:||||||||.
Zfish   196 KFKIKIMSELVSNGVQIYQFPTDDEAVTEINSSMNAHLPFAVVGSVEEVKVGNKTVRARQYPWGV 260

  Fly   262 VQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQQTFE 326
            ||||||:|||||||||||||.||||:||:||.|||||||:.:||:|||.|.|.|::|.|.|:|:|
Zfish   261 VQVENESHCDFVKLREMLIRVNMEDLREQTHARHYELYRRCKLEEMGFKDTDPDSQPFSLQETYE 325

  Fly   327 AKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRKALE 391
            |||...|.:||.||||:|||||.:|||.||||||.|::||.|||:|||.|.|||||:||.|:.||
Zfish   326 AKRKEFLGDLQKKEEEMRQMFVNKVKETEAELKEKERELHEKFEQLKRMHQEEKRKVEEKRRELE 390

  Fly   392 EDYLDFQRRKQQLATAHHTLTLGKSKKK 419
            |:...|.|||    .|..||:|.:..||
Zfish   391 EEMNAFNRRK----VAAETLSLSQPLKK 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	197/267 (74%)
		PTZ00121	<285..393	CDD:173412	70/107 (65%)
septin8a	NP_001108589.1	CDC_Septin	39..307	CDD:206649	197/267 (74%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	49..56		5/6 (83%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	101..104		2/2 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	184..187		2/2 (100%)
		PTZ00121	<274..419	CDD:173412	90/145 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	393..420		10/26 (38%)