Protein Alignment Septin2 and Septin7

DIOPT Version :10

• Sequence 1: NP_524417.1
• Gene: Septin2 / 42438
• FlyBaseID: FBgn0014029
• Length: 419
• Species: Drosophila melanogaster
• Sequence 2: NP_033989.2
• Gene: Septin7 / 235072
• MGIID: 1335094
• Length: 437
• Species: Mus musculus
• Alignment Length: 410
• Identity: 172/410 - (41%)
• Similarity: 270/410 - (65%)
• Gaps: 17/410 - (4%)

  Fly    22 GHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFEST----PSPHTLPSVKL 82
            |:|||.:||:|:..|||:.||.|.:|.:||:|||||||:::||.|...|.    ||.....:|::
Mouse    29 GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPEYPGPSHRIKKTVQV 93

  Fly    83 KAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDS 147
            :.....::|..|:|.|||.||.|:||.::..:.::.|:||||::||:||..|.::.|..:.  |:
Mouse    94 EQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMP--DN 156

  Fly   148 RIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVH 212
            |:..|||||.|:|||||.||:..||:|..||||||:||||||::..|.|:||.:|::|:..:.:.
Mouse   157 RVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIK 221

  Fly   213 IYQFP-TDDETVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYPWGTVQVENETHCDFVKLR 276
            ||:|| ||||...:....:...:|.|||||...|:|..|.:|.||||||..:|||..||||..||
Mouse   222 IYEFPETDDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENGEHCDFTILR 286

  Fly   277 EMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSD-NK------PISFQQTFEAKRSNHLA 334
            .|||||:|:|:::.|:..|||.||.::|..:.::.||:: ||      |::   ..|.:|..|:|
Mouse   287 NMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLA---QMEEERREHVA 348

  Fly   335 ELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQR 399
            :::..|.|:.|:|..:||||..:||:||.:|..:.|::|::...:.::|||.|:..||:..:::.
Mouse   349 KMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEEEKANWEA 413

  Fly   400 RKQQLATAHHTLTLGKSKKK 419
            :::.|...:.:.||.|:|||
Mouse   414 QQRILEQQNSSRTLEKNKKK 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Septin2	NP_524417.1	CDC_Septin	40..308	CDD:206649	125/272 (46%)
		PTZ00121	<285..393	CDD:173412	37/114 (32%)
Septin7	NP_033989.2	CDC_Septin	47..317	CDD:206649	125/271 (46%)
		Interaction with SEPTIN12. /evidence=ECO:0000250|UniProtKB:Q16181	47..317		125/271 (46%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	57..64		5/6 (83%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	113..116		2/2 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01056	194..197		2/2 (100%)
		DUF4670	<328..433	CDD:464815	32/107 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..437		16/56 (29%)