Protein Alignment Stat92E and sta-2

DIOPT Version :10

• Sequence 1: NP_001262760.1
• Gene: Stat92E / 42428
• FlyBaseID: FBgn0016917
• Length: 818
• Species: Drosophila melanogaster
• Sequence 2: NP_001122963.1
• Gene: sta-2 / 3565291
• WormBaseID: WBGene00010251
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 130/601 - (21%)
• Similarity: 246/601 - (40%)
• Gaps: 119/601 - (19%)

  Fly   170 NVQNTGIASPALGMVTPKVE-LYEVQHQI-MQSLNEFGNCANAL--KLLAQNYSYMLNSTSSPNA 230
            :::::...|||    .|.|: .:..:|.: .::...|..||::|  ..:|||........:....
 Worm    10 DIESSSAFSPA----EPVVDGAFVSKHNLSAEAYQGFKECADSLLSGKIAQNEQLPFIQRTLQIC 70

  Fly   231 EAAYRSLIDEK------AAIVLTMRRSFMYYESLHEMVIHELKNWRHQQAQAGNGAPFNEGSLDD 289
            |....:..|||      ..:|..|::..:...:||...:|                 :.|  ||.
 Worm    71 ENVILNFEDEKQHLMSDVLLVWAMKQQKLSIATLHTQQLH-----------------YKE--LDL 116

  Fly   290 IQRCFEMLESFIAHMLAAVKELMRVRLVTEEPELTHLLEQVQNAQKNL----VCSAFIVDKQPPQ 350
            |...||.....:...|:.:..|.:.     .|.:.  .|:|.:..:||    :..:.||.:|||.
 Worm   117 INLQFEYFGELLQQTLSGLDYLKQY-----YPNVG--FEEVHSKVRNLTHYFLYYSIIVSRQPPS 174

  Fly   351 VM----------KTNTRFAASVRWLIGSQLGI--HNNPPTVECIIMSEIQSQRFVTRNTQMDNSS 403
            |:          ::...|...:|.|.||..||  :|....|.|.::::      .|....::|:.
 Worm   175 VIVKCGEAENHRRSRFWFNTEIRILGGSAFGIDTNNENSNVNCYLITD------ETAKQLLNNAY 233

  Fly   404 LSGQSSGEIQNASSTMEYQQNN-HVFSASFRNMQLKKIKRAEKKGTESVMDEKFALFFYTTTTVN 467
            |....|.|.....:|..:|:.: ....|.|.:|::.| |.|.::  :||..:::.|.:......|
 Worm   234 LDIFESEEFCIEPNTSTFQKKDARGIKAKFDDMKVAK-KVALRR--DSVATKRYCLCYNIQLQTN 295

  Fly   468 -DFQIRVWTLSLPVVVIVHGNQEPQSWATITWDNAFAEIVRDPFM-ITDRVTWAQLSVALNIKFG 530
             ..::....:|||..|:|....:.:  |.:..:.:||::||.|.. |...|:.|:::.||.:||.
 Worm   296 CGIELVGKKVSLPFAVLVGPKADVE--AKLFLERSFADLVRHPLSDIPTHVSCAEMADALEMKFQ 358

  Fly   531 S--------------CTGRSLTIDNLDFLYEKLQREERSEYITWNQFCKEPMPD----------- 570
            :              ...|...:.....|..:::...:. ::..:.|.|.|:.:
 Worm   359 AIIETPQKNTDGPSVVQPRKFNMQTKQHLVMRMKPNNQG-FLPLDNFMKLPVAEEFQHKKSASAE 422

  Fly   571 ---RSFTFWEWFFAIMKLTKDHMLGMWKAGCIMGFINKTKAQTDLLRSVYGIGTFLLRFSDSELG 632
               :...|::|||.:.::|..::..||..|.:.||.:|..|: ::||.: .....|:||||.|.|
 Worm   423 GDWKLVPFYDWFFKLAEITNKYLYSMWYDGLVYGFCSKEDAE-NILRCI-PRSVLLVRFSDIEYG 485

  Fly   633 GVTIAYVNENGLVT----MLAPWTARDFQVLNLAD-RIRDLDVLCWLHP--------SDRNASPV 684
            .:.|:..|.||.:.    ..|...||......|:: :..|:|:   ::|        ..||...:
 Worm   486 KIKISVKNRNGEIRHHWYEHADLNARSLNSELLSNHKFSDVDL---IYPDIDLEVALGGRNKPRI 547

  Fly   685 K--RDVAFGEFYSKRQ 698
            :  |::|..|.|...|
 Worm   548 RLPRNLAPDEIYFDNQ 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stat92E	NP_001262760.1	STAT_int	2..119	CDD:214942
		STAT_CCD	191..338	CDD:341075	30/159 (19%)
		STAT_DBD	342..502	CDD:341082	39/173 (23%)
		SH2_STAT_family	578..696	CDD:198175	37/132 (28%)
sta-2	NP_001122963.1	SH2_STAT_family	433..545	CDD:198175	33/116 (28%)