Protein Alignment CG4360 and ZNF107

DIOPT Version :10

• Sequence 1: NP_650879.1
• Gene: CG4360 / 42413
• FlyBaseID: FBgn0038787
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001374954.1
• Gene: ZNF107 / 51427
• HGNCID: 12887
• Length: 896
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 144/439 - (32%)
• Similarity: 206/439 - (46%)
• Gaps: 52/439 - (11%)

  Fly   129 SEEEVVVDDPRKKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDKAFRQISTLTNHVKIHT 193
            :.:::::::  |..:|..|...|.|.:||..|..|||.|:|||||.|.|||.|.|.||.|.||||
Human   430 AHKKILMEE--KPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHT 492

  Fly   194 GEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQ-PQTGSGKHRKSQMHQAYQQQHQ 257
            .||.:.|..|.|.|.|.|.||||.|.:...:.        |: .:.|...:|.|.:     .:|:
Human   493 AEKSYKCEECGKAFNQHSNLINHRKIYSGEKP--------YKCEECGKAFNRSSTL-----TRHK 544

  Fly   258 RVQISKTLYSGSYSSPAAEELVKPFQCSVCKRRFPQLSTLHNHERTHIDPKPYKCETCDKSFSQL 322
            ::...:                ||::|..|.|.|.|.|.|..|::.|...||||||.|.|:|::.
Human   545 KIHTGE----------------KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKCEECGKAFNRF 593

  Fly   323 ATLANHKKIHTGDKPYTCSYCHMQFRQQSTLTNHLKTHTHQIAPGGVGGAGGGGGAVTATVDHSM 387
            :||..||:||||:|||.|..|...|.|...||.|...||.:    .:......|.|...:...::
Human   594 STLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKE----KLNKCEEFGKAFKQSSHRTI 654

  Fly   388 PAPLAPGTQ-----------QLTSGLLPNNLHGSTANIIQLDHHPLLHFLDGSTTVSSVVATAAA 441
            ...:..|.:           ..:|.|....:..:..|:.:.:.|.....|..:.|...::.|...
Human   655 HKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEK 719

  Fly   442 NTKVEHFQAGGSPSGRMTVVGTINMLKGDNPDRPFGCSVCQRFFSQQSTLVNHIKTHTGEKPYKC 506
            ..|.|......:....:|:...|:     ..::|:.|:.|.:.|:..|||..|...|||||||||
Human   720 PHKCEECGKAYNRFSNLTIHKRIH-----TGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKC 779

  Fly   507 KICEVNFRQVATLNNHMKIHTGEKPYNCSFCPKQFRQKSTLQNHLRVHT 555
            |.|...|...:||..|.|||||||||.|..|.|.|.|.|.|..|.::||
Human   780 KECGKAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHT 828

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4360	NP_650879.1	C2H2 Zn finger	144..164	CDD:275368	7/19 (37%)
		zf-H2C2_2	157..181	CDD:463886	15/23 (65%)
		C2H2 Zn finger	172..192	CDD:275368	12/19 (63%)
		C2H2 Zn finger	200..220	CDD:275368	11/19 (58%)
		zf-C2H2_8	281..366	CDD:464935	39/84 (46%)
		C2H2 Zn finger	284..304	CDD:275368	8/19 (42%)
		C2H2 Zn finger	312..332	CDD:275368	9/19 (47%)
		zf-H2C2_2	325..349	CDD:463886	13/23 (57%)
		C2H2 Zn finger	340..360	CDD:275368	7/19 (37%)
		C2H2 Zn finger	478..498	CDD:275368	7/19 (37%)
		C2H2 Zn finger	506..526	CDD:275368	8/19 (42%)
		zf-H2C2_2	519..543	CDD:463886	15/23 (65%)
		C2H2 Zn finger	534..554	CDD:275368	8/19 (42%)
ZNF107	NP_001374954.1	KRAB	48..108	CDD:214630
		C2H2 Zn finger	191..211	CDD:275368
		C2H2 Zn finger	219..239	CDD:275368
		COG5048	243..621	CDD:227381	82/221 (37%)
		C2H2 Zn finger	247..267	CDD:275368
		C2H2 Zn finger	275..295	CDD:275368
		C2H2 Zn finger	303..323	CDD:275368
		C2H2 Zn finger	331..351	CDD:275368
		C2H2 Zn finger	359..379	CDD:275368
		C2H2 Zn finger	387..407	CDD:275368
		C2H2 Zn finger	415..435	CDD:275368	0/4 (0%)
		C2H2 Zn finger	443..463	CDD:275368	7/19 (37%)
		C2H2 Zn finger	471..491	CDD:275368	12/19 (63%)
		C2H2 Zn finger	499..519	CDD:275368	11/19 (58%)
		C2H2 Zn finger	527..547	CDD:275368	4/24 (17%)
		COG5048	551..>863	CDD:227381	96/287 (33%)
		C2H2 Zn finger	555..575	CDD:275368	8/19 (42%)
		C2H2 Zn finger	583..603	CDD:275368	9/19 (47%)
		C2H2 Zn finger	611..631	CDD:275368	7/19 (37%)
		C2H2 Zn finger	639..659	CDD:275368	2/19 (11%)
		C2H2 Zn finger	699..715	CDD:275368	2/15 (13%)
		C2H2 Zn finger	723..743	CDD:275368	2/19 (11%)
		C2H2 Zn finger	751..771	CDD:275368	7/19 (37%)
		C2H2 Zn finger	779..799	CDD:275368	8/19 (42%)
		C2H2 Zn finger	807..827	CDD:275368	8/19 (42%)
		C2H2 Zn finger	835..855	CDD:275368
		C2H2 Zn finger	863..883	CDD:275368