Protein Alignment Orp8 and LOC3289987

DIOPT Version :10

• Sequence 1: NP_001189250.2
• Gene: Orp8 / 42412
• FlyBaseID: FBgn0261550
• Length: 990
• Species: Drosophila melanogaster
• Sequence 2: XP_061508394.1
• Gene: LOC3289987 / 3289987
• VectorBaseID: AGAMI1_008818
• Length: 815
• Species: Anopheles gambiae
• Alignment Length: 869
• Identity: 223/869 - (25%)
• Similarity: 353/869 - (40%)
• Gaps: 246/869 - (28%)

  Fly    45 QQGAAGGGDTLAHPATPHSHSMPGTPHQQPQSSSV--PTGGHLLQLQAPLPSAGGGTGAGAVTPS 107
            ||...|.|.|.|                  |||::  .|||           .|||.|      |
Mosquito   110 QQYNYGSGSTSA------------------QSSAMGFTTGG-----------VGGGPG------S 139

  Fly   108 GLSMGASNQSLGVSVGAASSVSGISITPPNSAGLRQSTVFDFKFKRRPSLKVLM----TKLPS-T 167
            |:..|....|:|   |.:||..|.||...|:.     .:||.|.....:...||    |||.: .
Mosquito   140 GVGAGGGTGSVG---GGSSSTPGTSIRRSNNL-----VLFDRKVTEADAFLQLMIDQTTKLEARL 196

  Fly   168 DSLSNSPAPSSPGIANWASDNRDGNVADKSAADAAKLNRKESYKAQRKNYRRE------KKRVAS 226
            ::|.::                      :.|.....:|  |...|...|.:..      .|..|:
Mosquito   197 ETLGDT----------------------EEATQLKTIN--EHVNAMLDNIKHSIVLLQIAKNTAN 237

  Fly   227 ELMNSLQDPAVIVLADWLKVRGTLKSWTKLWCVLKPGLLLIYKSQKTKSSHWVG---TVMLTSCQ 288
            .:....|.|.            :.||.|              :::.::|...||   |.:.|..:
Mosquito   238 PINGIYQGPI------------SSKSET--------------ETEPSESGLVVGVMSTSLPTDIE 276

  Fly   289 VIE--RPSKKDGFCFKLFHPLEQSIWAPRGPDKETIGAVVQPLPTAYLIFRAPSQAAGK-CWMDA 350
            |.:  |.|.:                      :..|.::..| .|:|      |.:.|: .:.||
Mosquito   277 VADECRESSR----------------------RANIASISVP-ETSY------SSSEGEDDFFDA 312

  Fly   351 LELSLRCSALLLRSNSSTGTAPTSSYIGEPLPVSHETQWSEADYEKHFNDHDLDADSQNEAPNAV 415
            .:.....|.|   :..::.|...|.:.|.   :|.|.|::.|:      |...::..:.:..:|.
Mosquito   313 NDSPFTSSQL---NTPTSNTRTLSEHTGR---LSGEEQYASAE------DSTSNSLKKQDTISAG 365

  Fly   416 MSGLESE------SESDPAEPAQDDV----------VDQQCVETSYVPFTEEEFGE-------QG 457
            .|||.:.      .:..|..|...:.          |.::..::..:|...:  |.       :.
Mosquito   366 QSGLVAPLLVGTGGDGVPTRPTLHETGLPAAVSGTGVPRRSYDSKALPIRTD--GSLDYDALYED 428

  Fly   458 EQVEELA-EENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDSYYHADLLSKAVQEDD 521
            |...:|: |.:.|::..::.||:.||||:||||||||||.||.|:..:|.:.|.||..:.....:
Mosquito   429 ESDNDLSMESHGSVVTHLLSQVKIGMDLTKVVLPTFILERRSLLEMYADYFAHPDLFLRIADLKE 493

  Fly   522 AFTRMKLVVQWYLSSFY--KKPKGLKKPYNPILGERFRCYW---QHPSG---------------- 565
            ...||..||:||||:::  :|....||||||||||.|:|:|   :.|:|
Mosquito   494 PRERMIQVVRWYLSAYHAGRKSSVAKKPYNPILGEIFQCHWDIPELPTGDEATNVEVKDGPVPWC 558

  Fly   566 --SRTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSKFYGNSTSAVLEGAATMTLLPRGEC 628
              .:..:||||||||||:||||..:.....|.:..:..||||.|.|......|..|:||....|.
Mosquito   559 RRDQLTFIAEQVSHHPPISAFYAEHYNKKISFSAHVWTKSKFLGLSIGVHNIGQGTVTLCDLNEE 623

  Fly   629 YTATTPYAHCKGILMGTLS-MELGGKINIECENTGYRTELEFKLKPFLGGADATNVVVGKI--KL 690
            |..|.|..:.:.||  |:. :||||.:.|.|..||||.:::|..|||.||  ..|.:.|:|  ..
Mosquito   624 YIVTFPNGYGRSIL--TIPWIELGGTVTITCPQTGYRADIDFITKPFYGG--KKNRIQGEIYGPN 684

  Fly   691 GKETLATINGHWD--KECRVKD-SKTGEETVLFKVDAETRSKRLTRYMVPLDLQEANESQRLWQR 752
            .|::..:|:|.|.  .|.:..| ||..:......|::....|:..|   |:..|:.|||:::|:.
Mosquito   685 DKKSFISISGEWSGLMEYKYNDGSKPSKFETFVDVNSIPIFKKKVR---PVAEQDENESRKVWRE 746

  Fly   753 VSEAIANEDQVAATEEKTVLEERQRADAKERLSSDSVHMPDLFELDSYGQWLYKYADLRPWDSRN 817
            |:..:...|...||..|..:|::||.:||||             .:::|:|..||
Mosquito   747 VTAGLKANDIEKATNAKFQVEQKQREEAKER-------------KETFGEWDTKY---------- 788

  Fly   818 DVRQYECQFKVLTQTRHKSVPIVH 841
                    ||.:.::...:.|::|
Mosquito   789 --------FKGIGESWIYTTPLLH 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orp8	NP_001189250.2	PH_OPR5_ORP8	231..361	CDD:270103	22/135 (16%)
		Oxysterol_BP	471..817	CDD:460126	131/374 (35%)
LOC3289987	XP_061508394.1	None