Protein Alignment Orp8 and osbpl10a

DIOPT Version :10

• Sequence 1: NP_001189250.2
• Gene: Orp8 / 42412
• FlyBaseID: FBgn0261550
• Length: 990
• Species: Drosophila melanogaster
• Sequence 2: XP_073787438.1
• Gene: osbpl10a / 100334085
• ZFINID: ZDB-GENE-170215-3
• Length: 798
• Species: Danio rerio
• Alignment Length: 529
• Identity: 163/529 - (30%)
• Similarity: 248/529 - (46%)
• Gaps: 82/529 - (15%)

  Fly   317 PDKETIGAVVQPLPTAYLIFRAPSQAAGKCWMDALELSLRCSALLLRSNSSTGTAPTSSYIGEPL 381
            |.:.::..:.|.|    |:.:|.|.|...|..:.|.:..:.:.   .:|:|:.:|| :::..:.:
Zfish   304 PTRGSVSCLDQDL----LLLKATSAATLSCLGECLTILQQSAG---HNNNSSSSAP-AAHNRDNV 360

  Fly   382 PVSHETQWS---EADYEKHFNDHDLDADSQNEAPNAVMSGLESESESDPAE--PAQDDVVDQQCV 441
            ||     |:   ....|:..|....:..|...:|......|...:| |..|  ...::|:|..
Zfish   361 PV-----WTVPKSPSGERLRNGGAANLCSTEPSPTFRKKSLLQNTE-DGMELISPDEEVLDSD-- 417

  Fly   442 ETSYVPFTEEEFGEQGEQVEELAEENKSLIWCIVKQVRPGMDLSKVVLPTFILEPRSFLDKLSDS 506
                 ..|||:.|        :.||.:|:|..::.|::.||||::|||||||||.||.|:..::.
Zfish   418 -----DNTEEDLG--------VLEEERSVILHLLSQLKLGMDLTRVVLPTFILEKRSLLEMYANF 469

  Fly   507 YYHADL---LSKAVQEDDAFTRMKLVVQWYLSSFYKKPKG--LKKPYNPILGERFRCYWQHPSGS 566
            ..|.||   :|..|..::   ||...|::|:::|::..||  .||||||:|||.|||.|:.|...
Zfish   470 MAHPDLFLSISAGVTAEE---RMVRFVEYYMTAFHEGRKGAVAKKPYNPVLGETFRCSWEVPQEK 531

  Fly   567 ---------------------------RTFYIAEQVSHHPPVSAFYVTNREDGFSITCSILAKSK 604
                                       |..::||||||||||||||....|.|..:...:..|||
Zfish   532 VRPLRTPGTGPKETANEEGVGAESECYRVHFVAEQVSHHPPVSAFYCECAERGMCVNTHVWTKSK 596

  Fly   605 FYGNSTSAVLEGAATMTLLPRGECYTATTPYAHCKGILMGTLS-MELGGKINIECENTGYRTELE 668
            |.|.|....:.|...:.|...||.|..|.|.|..:.||  |:. :|||||..|.|..:||...:.
Zfish   597 FMGMSVGVSMVGEGVLYLRDHGEEYVFTFPSAFARSIL--TVPWVELGGKATISCAKSGYSASVT 659

  Fly   669 FKLKPFLGGADATNVVVGKIKLGKE--TLATINGHWDKECRVKDSKTGEETVLFKVDAETRSKRL 731
            |..|||.||  ..:.|..::|....  .:....|.|:.......| :||..|:.........||:
Zfish   660 FHTKPFYGG--KLHRVSAEVKQNSSGTVVCKAQGEWNGTLEFTYS-SGETKVIDTTKLPVIRKRI 721

  Fly   732 TRYMVPLDLQEANESQRLWQRVSEAIANEDQVAATEEKTVLEERQRADAKERLSSDSVHMPDLFE 796
            .    |::.|...||:||||.|:||:...:...|||.|.:|||.||::.|:|.:.:....|..|.
Zfish   722 R----PVEKQSRRESRRLWQHVTEALKEGNVDLATEHKHLLEEDQRSEEKQRAADNMPWKPKYFS 782

  Fly   797 LDSYGQWLY 805
            .:..| |:|
Zfish   783 KEGDG-WVY 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Orp8	NP_001189250.2	PH_OPR5_ORP8	231..361	CDD:270103	9/43 (21%)
		Oxysterol_BP	471..817	CDD:460126	130/370 (35%)
osbpl10a	XP_073787438.1	None