Protein Alignment Nlg4 and alpha-Est7

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: NP_524261.1
• Gene: alpha-Est7 / 40901
• FlyBaseID: FBgn0015575
• Length: 572
• Species: Drosophila melanogaster
• Alignment Length: 730
• Identity: 165/730 - (22%)
• Similarity: 253/730 - (34%)
• Gaps: 307/730 - (42%)

  Fly    43 IVQTRYGRLHGL------ILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISD 101
            :..|.||::.|:      .:|..||.         |:|||.||..:.||...:.|.||:  |:.|
  Fly    34 VADTEYGQVRGIKRLSLYDVPYFSFE---------GIPYAQPPVGELRFKAPQRPIPWE--RVRD 87

  Fly   102 KYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEKKLPV 166
                 |.|               ||.:...::.:...:|. |||||||||::  |....:|..||
  Fly    88 -----CSQ---------------PKDKAVQVQFVFDKVEG-SEDCLYLNVYT--NNVKPDKARPV 129

  Fly   167 IVFIHGESF-------EWSSGNPYDGSVLASYG-------EVVVVTLNYRLGILGFLNANPNPHA 217
            :|:|||..|       ||             ||       :||:||:.||||.|||::.. :|..
  Fly   130 MVWIHGGGFIIGEANREW-------------YGPDYFMKEDVVLVTIQYRLGALGFMSLK-SPEL 180

  Fly   218 HARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILM 282
            :. ..|.||.||:.||.||:.|...||||||.:|:.|...|.|..:|:|.: ...:|||||.||.
  Fly   181 NV-PGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGESAGGASTHYMMLT-DQTQGLFHRGILQ 243

  Fly   283 SGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLT- 346
            ||||...||...|......::||.|.....|    :.:.:::.|::|..:||...:   .|.||
  Fly   244 SGSAICPWAYNGDITHNPYRIAKLVGYKGED----NDKDVLEFLQNVKAKDLIRVE---ENVLTL 301

  Fly   347 ---------SFGPSVDG------VVIRP-----------------GHSNLD-------------- 365
                     :||||::.      |:.:|                 |:::.:
  Fly   302 EERMNKIMFAFGPSLEPFSTPECVISKPPKEMMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQV 366

  Fly   366 ---ID--------DLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGA 419
               :|        :|:|....:...||
  Fly   367 LQQLDAGTPFIPKELLATEPSKEKLDS-------------------------------------- 393

  Fly   420 GTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEY 484
                                 |.....|:.
  Fly   394 ---------------------WSAQIRDVH----------------------------------- 402

  Fly   485 TDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSS--SSTAGSPGANAAASTS 547
                ||...  :|.|..:...|...||.|.:|.           |.|  :..||:|
  Fly   403 ----RTGSE--STPDNYMDLCSIYYFVFPALRV-----------VHSRHAYAAGAP--------- 441

  Fly   548 AGSTQPSGRCYFYVFDYQTKDGDYPQRM--------GTVHGEDLPYIFGAPLVDGFSHFPQNYTK 604
                     .|||.:|:.:::..:|.|:        |..|.:||.|.|.:.|........:.|..
  Fly   442 ---------VYFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRN 497

  Fly   605 SETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQ----------- 658
            .|..:.     .||.||.|||           |.|::.|...::|   .||:.:
  Fly   498 IERTVG-----IWTQFAATGN-----------PYSEKINGMDTLT---IDPVRKSDEVIKCLNIS 543

  Fly   659 ---KYLEIGMKPRIK 670
               |::::...|::|
  Fly   544 DDLKFIDLPEWPKLK 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	165/730 (23%)
alpha-Est7	NP_524261.1	COesterase	34..514	CDD:395084	156/681 (23%)