Protein Alignment Nlg4 and LOC1271033

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_309775.5
• Gene: LOC1271033 / 1271033
• VectorBaseID: AGAMI1_013832
• Length: 580
• Species: Anopheles gambiae
• Alignment Length: 739
• Identity: 178/739 - (24%)
• Similarity: 257/739 - (34%)
• Gaps: 265/739 - (35%)

  Fly     8 LLLRLLLLPTVLISWMHCAGASTADIYK-GARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFL 71
            ||:::||| ||:......|.:...::.: ||..|........||           :|.:    ||
Mosquito    15 LLVQILLL-TVMTDQGVEASSPIVNLAELGALRGSTGTSAWTGR-----------KFYQ----FL 63

  Fly    72 GVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLL 136
            ||.||...:.:|||.|....|||.||:.:.::...|||                      ||.|.
Mosquito    64 GVHYAQTTSGKNRFRPPIKVAPWQGIKDATRHGMPCPQ----------------------LKLLS 106

  Fly   137 PF----LENQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESFEWSSGNPYDGSVLASYGE---- 193
            .|    .....||||.|:::|...|.    |.||:|||||..|       |:|......||
Mosquito   107 LFTCKAFAGDPEDCLTLSIYSSDLAA----KRPVMVFIHGGGF-------YEGCAKNQTGEYLME 160

  Fly   194 --VVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHG 256
              ||:||:.||||.||||..:..    :...|.||||...||.|:|::|.:|||||.:|||.|..
Mosquito   161 RDVVLVTIQYRLGPLGFLQTDTG----SIPGNMGLMDMKLALEWVQEHIGRFGGDPANVTLFGQS 221

  Fly   257 TGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDDINRHHEQ 321
            .|||.|:.|:.||.:..||||:.||.|..:.:.|....:|:.....||.|..    ::.:...|:
Mosquito   222 AGAAAISALLYSPQVPDGLFHKVILQSAGSSAPWVWDREPLQSVRDLAFEAG----EEFDAPEEE 282

  Fly   322 I------VDC------------------------------------LRDVPLEDLYLADIQAPNF 344
            |      ||.                                    |...|||.:....:: ||.
Mosquito   283 IDTFYQNVDVWKLLQVFNEYKVKTTLESGLDRVGGNRLVTGDWERYLPQTPLECMKQGKVR-PNI 346

  Fly   345 LTSFGPSVDGVVIRPGHSNL-----------DIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAG 398
                 |.:.||....|...|           .:|||.........|.|.|.
Mosquito   347 -----PMMAGVTKHEGTFLLTTVYDHFKRTGKLDDLTFMKYGLMDAVSKFL-------------- 392

  Fly   399 GGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRT 463
                 |:|....|.:.|            |.:       .|:  |::.::::|..||..|.:|
Mosquito   393 -----GAGDDPTGAFVG------------YQM-------RSL--FTSKELESGSFGEMADGLI-- 429

  Fly   464 YVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPP 528
                                               |.|...|    ..||::|...
Mosquito   430 -----------------------------------DLAGTIL----IKAPLLREAQ--------- 446

  Fly   529 VSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDY---QTKDG------DYPQRMGTVHGEDLP 584
                       |||..:.:|        .|.|.|||   .::.|      .||...|..|.:|..
Mosquito   447 -----------ANARVNPNA--------TYLYTFDYVGEHSRFGYGNDTSHYPFGGGVHHSDDKL 492

  Fly   585 YIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSIT 649
            |:|..|     ...|....:.:||:::.::..||:||..|.|....               .::.
Mosquito   493 YLFPYP-----PGKPDALNERDTAMAKLMVDLWTSFAAEGVPKSDR---------------LTVP 537

  Fly   650 WENYDPLHQKYLEIGMKPRIKNHF 673
            |.........||.|...|.:.::|
Mosquito   538 WNPMTAYAGPYLHINDPPSVGDNF 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	167/703 (24%)
LOC1271033	XP_309775.5	None