Protein Alignment Nlg4 and LOC1270129

DIOPT Version :10

• Sequence 1: NP_001369025.1
• Gene: Nlg4 / 42402
• FlyBaseID: FBgn0083975
• Length: 1437
• Species: Drosophila melanogaster
• Sequence 2: XP_308801.4
• Gene: LOC1270129 / 1270129
• VectorBaseID: AGAMI1_007698
• Length: 641
• Species: Anopheles gambiae
• Alignment Length: 800
• Identity: 178/800 - (22%)
• Similarity: 297/800 - (37%)
• Gaps: 245/800 - (30%)

  Fly     4 SQLLLLLRLLLLPTVLISWMHCAGASTADIYKGARLGH---RIVQTRYGRLHGLILPLDSFRFLR 65
            ::|:|||.||           |.|.          ||.   .:.....|.:.|:.:.:  ||..|
Mosquito    13 TRLVLLLALL-----------CRGG----------LGRDPPTVTIPDQGTVMGMYMKM--FRTQR 54

  Fly    66 SVEVFLGVPYATPPTKQNRFSP---TRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKG 127
             |..:||:|||..|..:.||:|   ...|: |:|::.:...:|.|              ..||:.
Mosquito    55 -VVAYLGIPYAQAPVNEKRFTPPVVDNLPS-WEGVKNATSSAPHC--------------WHMPRD 103

  Fly   128 RLEYLKRLLPFLE-----------------NQSEDCLYLNVFSPVNAGANEKKLPVIVFIHGESF 175
            ......:|  |:|                 ...||||:||::.|.:....:....::.|..|: |
Mosquito   104 THRRHNQL--FMELIRSGDDGGGGDGGGDRQYDEDCLFLNIYIPDSTMPTDGYSVLVTFPTGD-F 165

  Fly   176 EWSSG---NPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQ 237
            :..:.   ||:.   :....:::|||:.|||||.||..:...    ....|:|||||.|||.||:
Mosquito   166 DGDTPFTLNPFQ---MVFKQKIIVVTVAYRLGIFGFFTSMDG----EAPGNFGLMDQSAALLWIK 223

  Fly   238 QNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRGLFHRAILMSGSAYSSWALVEDPVLFAIK 302
            :||:.|.|:..|||:.||||||.|:...:||......:||:|||||||     .|::..|..|.:
Mosquito   224 RNIRLFNGNEGSVTIMGHGTGAVCVGLHLTSGDWTDDMFHKAILMSGS-----LLLDSSVRTAKQ 283

  Fly   303 LAKEVN--CTIPDDINRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVD-GVVIRPGHSNL 364
            .|..::  .|......|...:::||||.|.      |.|.|.|     .|.:| |.||..|.||.
Mosquito   284 YASSLDELATAFGCFRRPTTKLMDCLRRVD------AQILAEN-----SPPIDWGPVIDQGLSNT 337

  Fly   365 ------DIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMN 423
                  |..:::....:......
Mosquito   338 TTPFIPDHPNMLVHQGKLRRVPL------------------------------------------ 360

  Fly   424 MGGHYDVLFGVVTGESIWRFSAHD-IQNGFEGERRDKIIRTYVRN-----AYNY-----HLNEIF 477
            :.||.|:       |.:...:..| :::|...|..|.::...|.:     .:|.     :::.:.
Mosquito   361 LIGHTDM-------EEVLELTMGDMLEHGLGAEMFDTLLGDVVMSDLAEMEFNETLCGGNMDIVM 418

  Fly   478 YTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANA 542
            ..:..:|..:..|:: |:..|...:...::.::|||.:.    ||.:               .:.
Mosquito   419 EAVQYQYKPYPPTTE-PLALRRKYIEFATERKYVAPTIE----LAMH---------------MSQ 463

  Fly   543 AASTSAGSTQPSGRCYFYVFDYQTKDG----DYPQRMGTVHGEDLPYIFGAP----LVDGFSHFP 599
            .|.|           :.|.||.:.:..    |.|:.:|..|..:|.:::|.|    |.|     .
Mosquito   464 QADT-----------FVYRFDIKPRTAAALKDVPEWVGVPHNFELIFLWGLPYWLALAD-----Q 512

  Fly   600 QNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIG 664
            ..:..::..:::.||..|.|||:..||.:       :.|        .|.||.:.......|.|.
Mosquito   513 MQWDSADKRVADIVMTLWANFAKFTNPTQ-------VGV--------YIRWEKFTVTEPGVLIID 562

  Fly   665 MKPRIKNH----FRAHQLSIWLRLIPELHRAGMEDVIARHNLFRNHDDMDLYEGPVKPDPFGIST 725
            ....:.:|    |.|  :..|....|.:.....:...|.:|                    |...
Mosquito   563 RSFNMSDHTTMSFDA--VKFWNHYYPSVINFAAQCCNATYN--------------------GAER 605

  Fly   726 AAGASGSSSSSSSSSRLLLV 745
            .|..|||..:....:.|:|:
Mosquito   606 GAPLSGSLVAGLLLANLILL 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nlg4	NP_001369025.1	COesterase	43..681	CDD:395084	157/692 (23%)
LOC1270129	XP_308801.4	None