Protein Alignment CG4465 and slc22a15.2

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001039179.1
• Gene: slc22a15.2 / 734018
• XenbaseID: XB-GENE-5824718
• Length: 487
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 126/563 - (22%)
• Similarity: 214/563 - (38%)
• Gaps: 123/563 - (21%)

  Fly    59 DDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMAC--ILFTAPDLYPEEEYKCDTTAFGPDVNST 121
            |:...:| |.||..|.|....|.|.::    ::||  :|.......||
 Frog     4 DEAFLYI-GEFGCCQKRLTAFLTLLQV----YVACQSMLIVLVGAVPE----------------- 46

  Fly   122 VSLDHCYVMVNYGESAYAMRQCRKFLY-TTGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGV 185
                  |::.|...|| :..:..|.|: |..|.|:..|:.|:....:.|..:......|||||.:
 Frog    47 ------YLIDNEDISA-SKEEYTKHLHDTNNFTSIVSEWHLIKNEAYKVNLASSLFFAGLLIGNI 104

  Fly   186 AATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIFGDITA 250
            ....|...|..|.:|.:|::              |.:..|. |.|......:....::..|.:..
 Frog   105 LFGPLSDKLGRRPVYLSGLF--------------FDITFGY-CTALAPSYEVFAVSRFFVGIMNG 154

  Fly   251 GKYRVGTLILYD----CFWAL-----GLILLPGLASNAPSWQHIYLGVTLSLL-----VIVFLLP 301
            |...|..::..:    .:|||     .||...|:|..|....:|....||:.:     :..|||.
 Frog   155 GMALVSFVLTQEYVGKSYWALTGSLTNLIFAVGIAFYALLGFYIRNWRTLAFVANSPGIFFFLLS 219

  Fly   302 W-TPDSPRWQLQH--TKEAQLAIERTVGILLEAARTNGRMHKV--SKELPQQLEELRERMLEPMP 361
            : .|:||||...|  |.||:       |:|...|..||....|  .|..|....:....:.:.:.
 Frog   220 FLLPESPRWLYSHGYTTEAE-------GVLQSMAVGNGVERPVVKLKSCPGTSSKSAHSVFDLVK 277

  Fly   362 --AVHW-----MHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVRSFGREHLVSNTLAMGLAE 419
              .:.|     |::|       :....|:..|    .:|.|.|       :.:|..|....||.|
 Frog   278 YGVLRWRTILLMYIW-------YVCSLVYYGL----TLNAGEL-------KGNLYLNVALYGLVE 324

  Fly   420 MLGCFLALHLTFNLSERKW----QWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLG-LLMASLP 479
            :....|.|:..    |:.|    :...||   :|..|..|.|..  .:||..|..|. .::|...
 Frog   325 VPAFPLCLYFI----EKSWSGRRKATAGF---LGFAGFACIFTI--FLPETNGDLLNPTVLALFG 380

  Fly   480 QAAVACAQSMILACLGELVPMEQRSC-LSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLV 543
            :.:|:.|.:::.....||.|...|:. |...|:. .|...:.:.|:..::.::|::...||.:..
 Frog   381 KLSVSAAFNVVYIYTSELYPTVVRNAGLGVCAMA-CRFGGILSPFIPTMKSLNPSMPFVAFGISG 444

  Fly   544 ILGGLGTCCL-VTRDKE--------QPPVGAVVNKGQQLIAFT 577
            |..|:.:..| .||:|.        |.|...::::|.:::|.|
 Frog   445 ISAGILSLLLPETRNKPIAESIEDLQSPAYQLLSRGNEVLAST 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	99/442 (22%)
slc22a15.2	NP_001039179.1	MFS	48..455	CDD:475125	102/457 (22%)