Protein Alignment CG4465 and Slc22a16

DIOPT Version :9

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 605
• Identity: 120/605 - (19%)
• Similarity: 203/605 - (33%)
• Gaps: 203/605 - (33%)

  Fly    57 NDDDVITHIMGNFGPWQLRSLLI---------------LFL-------CKIP-----------AA 88
            |.:.:..|| |:||.:|:...||               :||       ||.|           :|
Mouse     5 NVELIFDHI-GHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSA 68

  Fly    89 WFMACIL-FTAPDLYPEEEYKCDTTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRK------- 145
            |.:..|| ..:|      |:|                ||..|.:..|| .:.:.:|.:
Mouse    69 WRLEDILALRSP------EHK----------------DHIMVELQDGE-IWELTRCSRTWRENTS 110

  Fly   146 ---FLYTTGFH-----------------SLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKL 190
               :.|:...|                 |....|:|||...::....|...:||:::|.:.
Mouse   111 HLGYEYSGYKHDSPCFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSIT---- 171

  Fly   191 MRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMIT--------SGQYI--- 244
            ...||.|...|..:||..:.....|:...|...         ...||||        ||.::
Mouse   172 FSYLSDRFGRRMALWCTSIGVFFFGIASLFIFD---------YLSFMITRFFLVMASSGYFVVVF 227

  Fly   245 --FGDITAGKYRVGTLILYDCFWALGLILLPGLASNAPSW---QHIYLGVTLSLLVIVFLLPWTP 304
              ..:|...|.|....|..:.|:|:|.:|:...:....:|   |.|...||...::..::|   |
Mouse   228 VYVMEIIGKKARTWASIHLNTFFAIGAMLVALASYLLKTWWLYQIILCIVTTPFILCCWML---P 289

  Fly   305 DSPRWQLQ--HTKEAQLAIERTVGI-------------LLEAARTNGRM-HKVSKELPQQLEELR 353
            ::|.|.|.  ..||||..:: |:.:             .|:..|::.:. |.:.|   .:|.:|.
Mouse   290 ETPFWLLSEGRYKEAQGTVD-TMAVWNKSSSCDLVELLSLDVTRSHNKSPHSIRK---HRLADLF 350

  Fly   354 ERM-LEPMPAVHWMHLW----MG------------QRRSTFHLVAVHMALATFMVVNTGLLLHVR 401
            ..: :..|..:.|:. |    :|            :....:.|:...|.:..::.    |.:.::
Mouse   351 HNLDVAKMTLIVWLD-WFTANLGYYMFGKEVIRRKENEPLYLLLVGAMEIPAYIC----LCIWLK 410

  Fly   402 SFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEV 466
            ..||.   ...|...|...|.|.  ||:.                                ||..
Mouse   411 RVGRR---KTMLLFLLVSSLTCM--LHVV--------------------------------MPSD 438

  Fly   467 YGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQVS 531
            | .|...::|.|.::.::...:.|.....||.|...| ||:..:..  .|..:|:.|:......|
Mouse   439 Y-KTAKRMVALLVKSVISSVFAFIYLYTAELYPTTVR-CLAVGSSN--MVSHVSSIFIPFTSHFS 499

  Fly   532 PA---LSLSAFCLLVILGGL 548
            ..   |....|.:|.||.||
Mouse   500 KVWIFLPQILFGILAILSGL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	117/595 (20%)
		MFS	169..>303	CDD:119392	32/149 (21%)
Slc22a16	NP_081848.1	2A0119	14..535	CDD:273328	117/595 (20%)
		MFS	163..525	CDD:119392	85/423 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030