Protein Alignment CG4465 and Orct2

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_651238.2
• Gene: Orct2 / 42890
• FlyBaseID: FBgn0086365
• Length: 567
• Species: Drosophila melanogaster
• Alignment Length: 576
• Identity: 129/576 - (22%)
• Similarity: 224/576 - (38%)
• Gaps: 115/576 - (19%)

  Fly    59 DDVITHIMGNFGPWQLRSLLILFLCKIPAAW--FMACILFTAPDL-------------------- 101
            |:.|.| :|:||.:|.....::.|..||.|:  .....|...||.
  Fly     4 DEAIIH-LGDFGRYQKIIYFLICLTSIPVAFHKLAGVFLLAKPDFRCALPFENGSSYDLPTHLWN 67

  Fly   102 --YPEEEYKCDTTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRKFLYTTG--FHSLTMEFDLV 162
              |||.| :|...    ||:.|..    |:..:...|:...:.|..::|...  .:|...|::||
  Fly    68 LSYPENE-RCSYY----DVDYTEE----YLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLV 123

  Fly   163 CLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLR 227
            |..||..|.|....:.|:|:|.:...:|......:.|....:...::..:|.|:..::..:...|
  Fly   124 CGRDFMAATSDSLFMLGVLLGSIVFGQLSDKYGRKPILFASLVIQVLFGVLAGVAPEYFTYTFAR 188

  Fly   228 CLAAVSCCFMITSGQYIFGDITAGKY-----RVGTLILYDCFWALGLILLPGLASNAPSWQHIYL 287
            .:...:     |||.::...:.|.:.     |:...|....|:::|.:|....|.....|:.:.:
  Fly   189 LMVGAT-----TSGVFLVAYVVAMEMVGPDKRLYAGIFVMMFFSVGFMLTAVFAYFVHDWRWLQI 248

  Fly   288 GVTLSLLVIVFLLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQL--- 349
            .:||..|:.:|.....|:|.||.|...::     :..:..:.:|||.|  ..::|.|...:|
  Fly   249 ALTLPGLIFMFYYWIIPESARWLLLKGRK-----DCAIANMQKAARFN--KVEISDEALSELLDE 306

  Fly   350 ----EELRERMLE-------PMPAVHWMHLWMGQRRSTFHLVAVHMALATFMV---VNTGLLLHV 400
                ||..::.||       |.|:|..:..:...||.|.      :....::|   |..||..:.
  Fly   307 GENSEEKAKQKLEDQELDEGPPPSVWDLFCYPNLRRKTL------LIFLDWLVTSGVYYGLSWNT 365

  Fly   401 RSFGREHLVSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPE 465
            .:.|...|: |.:..|..| :..::.|.||.|    :|   |..:|:.||:             .
  Fly   366 SNLGGNVLL-NFVISGAVE-IPAYIFLLLTLN----RW---GRRSILCGCL-------------V 408

  Fly   466 VYGLTLGLLMASLPQ----AAVACA---QSMILACLG-------ELVPMEQRSCLSFSAVTWARV 516
            :.||:| |....:||    ..||||   :..|.|..|       |..|...|:....:|...||:
  Fly   409 MAGLSL-LATVIIPQRMHTLIVACAMLGKLAITASYGTVYIFSAEQFPTVVRNVALGAASMVARI 472

  Fly   517 WQLSASFLTLLRQVSPALSLSAFCLLVILGGLGTCCLVTRDKEQPPVGAVVNKGQQ 572
            ..:.|.||..|..:...|.|.....|.::.||  ..|:..:....|:...:..|::
  Fly   473 SGMMAPFLNFLATIWKPLPLLICGSLTLVAGL--LSLLLPETHNKPMLETIADGER 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	102/447 (23%)
Orct2	NP_651238.2	2A0119	11..520	CDD:273328	125/560 (22%)