Protein Alignment CG4465 and CG10486

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Alignment Length: 681
• Identity: 146/681 - (21%)
• Similarity: 242/681 - (35%)
• Gaps: 241/681 - (35%)

  Fly     2 KKDNLYRGWMPNIRR----NSPAPLDLGHMAH------SFTCTDPKANEVS---------PQTPH 47
            |:::..:|....:::    ..|..:|:|..|.      ..|..:|...|.|         .:|..
  Fly    19 KREHRDQGQQSKLKKIKYYIEPDKVDIGIQAGDSLEKVKVTYVEPDDEESSHGFFWGKKKSETSL 83

  Fly    48 PKANNLADDN-DDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACI-------LFTAPDLYPE 104
            |:.:...||. |.|.:..::|.||.:|:|    |||..||..:..|.:       ..|.|
  Fly    84 PRRSWETDDYIDFDDLLPMIGQFGRFQIR----LFLFMIPFCFITAFVYLGQIFMCLTPP----- 139

  Fly   105 EEYKCDTTAFGPDVNSTV---------------SLDHC------YVMVNYGE--SAYAMRQ---- 142
             :|.|    :.|::..|.               |...|      |..:::.|  |||....
  Fly   140 -KYYC----YVPELLHTPVELRKELSIPKEKDGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTI 199

  Fly   143 -CRK-FLYT---TGFHSLTMEFDLVCLCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRT 202
             |:| :::.   ..|.|.||||..:|..|.:..::|.....|.::||:|
  Fly   200 PCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLA---------------- 248

  Fly   203 GIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCF------MITSGQYIFGDITAGKYRVGTLILY 261
                          ...|:.||| |..|.||.||      :.||....|......::.||.  .|
  Fly   249 --------------YGHFADHCG-RVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGA--SY 296

  Fly   262 D-CFWALGLILL---------------------------PGLASNAPSWQHIYLGVTLSLLVIVF 298
            | ||..:.:::|                           |.:|.:|.:|:......:|.:::.:|
  Fly   297 DTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMF 361

  Fly   299 LLPWTPDSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQL---------EEL-- 352
            .....|:|.|| |....|...|:|    ||......|.:  :||||:....         |||
  Fly   362 SFCLLPESARW-LVSVGEIDKALE----ILKNVIEVNKK--QVSKEILDLFEASCTQFYKEELDG 419

  Fly   353 ----------RERMLEPMPAVHWMHLWMGQRRSTFHLVAVHMALATFMVVNTGLLLHVRS---FG 404
                      |:||...|  :..:.:||                 :..:|..|   |||:   ..
  Fly   420 RDFTVLSIFKRKRMARYM--ILMILIWM-----------------SISLVYDG---HVRAASVLD 462

  Fly   405 REHL-VSNTLAMGLAEMLGCFLALHLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYG 468
            .|:: :..|:|.. .|:.|..|.: ||.:.:.|:|                |.|. ...:..|:.
  Fly   463 SENIFLFFTIACA-TELPGNILVI-LTLDRAGRRW----------------CSFF-YTSLSGVFS 508

  Fly   469 LTLGLLM---ASLPQAAVA------CAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFL 524
            | ||...   |::..:|:|      ...::.|....|::|...|:    ..|.:..    :..|:
  Fly   509 L-LGASFQNRANMRMSALAGRFFSNICYNIGLQWAAEILPTVVRA----QGVAFIH----TMGFV 564

  Fly   525 TLLRQVSPAL------SLSAFCLLVILGGLG 549
            .:|  :||.:      |||:  .|::||.||
  Fly   565 AML--MSPPVVYLSKKSLSS--TLIVLGALG 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	106/485 (22%)
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	130/596 (22%)