Protein Alignment CG4465 and Slc22a14

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001032838.1
• Gene: Slc22a14 / 382113
• MGIID: 2685974
• Length: 629
• Species: Mus musculus
• Alignment Length: 583
• Identity: 131/583 - (22%)
• Similarity: 210/583 - (36%)
• Gaps: 174/583 - (29%)

  Fly    55 DDNDDDVITHIM---GNFGPWQLRSLLILFLCKIPAAWFMAC--ILFTAPDLYPEEEYKCDTT-- 112
            |...||....:|   |.||.:|.|.:::.|:..|.:.:|:..  .|.||...|      |:|:
Mouse    44 DARRDDKFASVMDAIGEFGTFQWRLVVLTFIPSILSTFFIFSHHFLLTAQRPY------CNTSWI 102

  Fly   113 -AFGPDVNSTVSLD------------HC--YVMV------------NYGESAYAMRQCR-----K 145
             ..||::.....|:            .|  |:.|            ||.|:      |:     .
Mouse   103 LEVGPNLTEDEQLNLTLPRAPNGSFLTCLMYIPVPWDLDSIIHFGLNYTET------CKFGWIYP 161

  Fly   146 FLYTTGFHSLTMEFDLVC---------LCDFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYR 201
            |.:|   .||..||||||         |..|         |.|:|.|.:    |...||.    :
Mouse   162 FAHT---RSLINEFDLVCGNEPNKENGLTVF---------LSGVLTGSL----LFGFLSD----K 206

  Fly   202 TGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFMITSGQYIF--------------------G 246
            .|.:.:::.|||..|:..|            ...|:.:..||:|                    .
Mouse   207 LGRYPIILLSLLGFLIFGF------------GTAFVSSFYQYLFFRFFVAQASVGYAICSVSLVM 259

  Fly   247 DITAGKYRVGTLILYDCFWALGLILLPGLASNAPSWQHIYLGVTLSLLVIVFLLPWTP------- 304
            :...|::|...:||...|..:|:|||.|||.....|:         ||.::..:|..|
Mouse   260 EWLVGEHRAQAVILQHSFLTIGVILLTGLAYKVVHWR---------LLCLLGGMPMFPLICNIWV 315

  Fly   305 --DSPRWQLQHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEELRERMLEPMPAVHWMH 367
              :||||.:...|     :|....:|..||..|      .|.:|..|  |.|..:..........
Mouse   316 LRESPRWLMVRGK-----VEEAKKVLCYAAEVN------KKTIPLNL--LNELQISGKKVAKASI 367

  Fly   368 LWMGQRRSTFHLV-AVHMALATFMVVNTGLLLHVRSFGRE----HLVSNTLAMGLAEMLGCFLAL 427
            |.....:..|.:| |:.....|...::..|.|.:..||.:    .:|.:.:|  :...|.|.:.|
Mouse   368 LDFCTNQHLFKVVLAIGCVWFTVSYISFTLNLKMNDFGLDVYFVQMVRSIVA--VPARLCCIILL 430

  Fly   428 HLTFNLSERKWQWAGGFAIVVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILA 492
            .. |.   |||    ...:.:..:.|:|.||.  .:|:....|: :|...|.:.::|...|:...
Mouse   431 EY-FG---RKW----ALNLTLFLVTSMCLFLL--FLPQEPKSTI-ILTLMLAEFSMAGTLSIFFI 484

  Fly   493 CLGELVPMEQRSC-LSFSAVTWARVWQLSASFLTLLRQVSPALSLSAFCLLVILGGLGTCCLV 554
            ...||:|...||. |...::.|...   :.|.:.:.:|....|.:...||         ||::
Mouse   485 YTAELLPTVLRSTGLGMVSLAWVAG---AISSVAIFKQTKTQLPIFFCCL---------CCVL 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	103/458 (22%)
Slc22a14	NP_001032838.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		2A0119	59..553	CDD:273328	127/568 (22%)