Protein Alignment CG4465 and SVOPL

DIOPT Version :10

• Sequence 1: NP_650847.1
• Gene: CG4465 / 42374
• FlyBaseID: FBgn0038750
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001132928.1
• Gene: SVOPL / 136306
• HGNCID: 27034
• Length: 492
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 117/564 - (20%)
• Similarity: 194/564 - (34%)
• Gaps: 168/564 - (29%)

  Fly    43 PQTPHPKANNLADDNDDDVITHIMGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEY 107
            ||...||...:     :|.:..|  .||.:.:...||:....:..|..:..|...:|.:..|.:.
Human    24 PQVKEPKTFTV-----EDAVETI--GFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQL 81

  Fly   108 KCDTTAFGPDVNSTVSLDHCYVMVNYGESAYAMRQCRKFLYTTGFHSLTMEFDLVCLCDFFVAWS 172
            :          |..|:|....|...|                       |.|.:
Human    82 E----------NWQVALVTTMVFFGY-----------------------MVFSI----------- 102

  Fly   173 QYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLAAVSCCFM 237
                |||||..                 |.|.|.:|:.|.|.|..  |||   |...|.....|:
Human   103 ----LFGLLAD-----------------RYGRWKILLISFLWGAY--FSL---LTSFAPSYIWFV 141

  Fly   238 I------------TSGQYIFGDITAGKYRVGTLILYDCFWALGLILLPGLAS---NAPSWQHIYL 287
            .            :.|..|..:....|||...|.|...||..|.:|:.||||   ....|:.:..
Human   142 FLRTMVGCGVSGHSQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTIGWRWLIR 206

  Fly   288 GVTLSLLVIVFLLPWTPDSPRWQLQ--HTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLE 350
            ..::..::::....:.|:|.|:.:.  :|:.|...:||       .|:.|..:....| |.:.:.
Human   207 VASIPGIILIVAFKFIPESARFNVSTGNTRAALATLER-------VAKMNRSVMPEGK-LVEPVL 263

  Fly   351 ELRERMLEPMPAVH-------WMHLWMGQRRSTFHLVAVHMALATFM-------------VVNTG 395
            |.|.|..:.:.|.:       |: :|:|   .:|....|.:|.|..:             ||.||
Human   264 EKRGRFADLLDAKYLRTTLQIWV-IWLG---ISFAYYGVILASAELLERDLVCGSKSDSAVVVTG 324

  Fly   396 -----------LLLHVRSFGREHLVS--NTLAMGLAEMLGC-FLALHLTFNLSERKWQWAGGFAI 446
                       ..:...|..|..::|  ..:|:....:||. ||...|:             .:|
Human   325 GDSGESQSPCYCHMFAPSDYRTMIISTIGEIALNPLNILGINFLGRRLS-------------LSI 376

  Fly   447 VVGCIGSICWFLAEEDMPEVYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAV 511
            .:||  :..:||.........|| :|.|.  :.:|.||...:.:.....|:.|...|:....::.
Human   377 TMGC--TALFFLLLNICTSSAGL-IGFLF--MLRALVAANFNTVYIYTAEVYPTTMRALGMGTSG 436

  Fly   512 TWARVWQLSASFLTLLRQVSPALS-LSAFCLLVILGGLGTCCLV 554
            :..|:..:.|.|::   ||..:.| |.|.||      ..:.|:|
Human   437 SLCRIGAMVAPFIS---QVLMSASILGALCL------FSSVCVV 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	MFS_SLC22	143..553	CDD:340875	96/461 (21%)
SVOPL	NP_001132928.1	MFS_SVOPL	49..480	CDD:341000	109/532 (20%)