DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4465 and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_650847.1	Gene:	CG4465 / 42374	FlyBaseID:	FBgn0038750	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	552	Identity:	125/552 - (22%)
Similarity:	206/552 - (37%)	Gaps:	105/552 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 MGNFGPWQLRSLLILFLCKIPAAWFMACILFTAPDLYPEEEYKC-----DTTAFGPDVNSTVSLD 125
            :|..|.:|:....:|.:..:    ||.|..|..........::|     |....|.|      .|
Frog    10 VGGLGRFQIIHTTMLLIPML----FMGCHNFLQNFSAAVPAHRCWVPSLDNNTMGYD------QD 64

  Fly   126 H--CYVMVNYGESAYAMRQCRKFL---YTTG-------------------FHS-LTMEFDLVCLC 165
            |  .::.::..|...:..:.||.|   :|.|                   |.| :..|:||||..
Frog    65 HLPAFIPMDESEKPLSCLRYRKALHSMWTNGTSTNHTEPCEDGWVYDKSDFSSTIVTEWDLVCKL 129

  Fly   166 DFFVAWSQYWHLFGLLIGGVAATKLMRVLSPRQIYRTGIWCLLMCSLLMGLVKDFSLHCGLRCLA 230
            ......:|..::.|:|:|.|....|...|..|.:.......:.:|......:.:|..:|..|||.
Frog   130 RKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVCGTCAAFLPNFITYCTFRCLC 194

  Fly   231 AVSCCFMITSGQYIFGDITAGKYR--VGTLIL--YDCFWALGLILLPGLASNAPSWQHIYLGVTL 291
            .::...:..:...:..:.|..|.|  :|||..  :.|    |.|||..||.....|:.:...|:
Frog   195 GIAFSGITLNTNSLILEWTPPKGRTIMGTLFAAGFTC----GQILLAALAYGIREWRWLQFAVS- 254

  Fly   292 SLLVIVFLLPW-TPDSPRWQL--QHTKEAQLAIERTVGILLEAARTNGRMHKVSKELPQQLEE-- 351
            :.....||..| .|:|.||.:  ..:.||..|::| |.|:      ||:     :|..|:|.|
Frog   255 APFYFFFLYSWLVPESARWLILKGRSHEALKALQR-VAII------NGK-----REEGQKLSEMI 307

  Fly   352 LRERMLEPMPAVHWMHLWM------GQRRSTFHLVAVHMALATFMVVNTGLLLHVRSFGREHLVS 410
            |...|...:..|...|...      |.|:.|..|:.|..:..   |...||.:.:::||    :|
Frog   308 LISHMQSELNQVKRPHSLFDLFRTPGMRKVTICLMMVWFSSG---VAFYGLGMDLQNFG----IS 365

  Fly   411 NTL---AMGLAEMLGCFLALHLTFNLSERKWQWA----GGFAIVVGCIGSICWFLAEEDMPE--- 465
            ..|   ..|..:|....:|..|...:..|..|..    .|.|::....           :|:
Frog   366 IFLLQFTFGAIDMPAKVVAALLMTYMGRRVTQATVLILSGVALLTNAF-----------IPQGMK 419

  Fly   466 VYGLTLGLLMASLPQAAVACAQSMILACLGELVPMEQRSCLSFSAVTWARVWQLSASFLTLLRQV 530
            :..:.|.:.......|:.|||...    .|||.|...|..........|||..:.|..:.||.::
Frog   420 ILRMVLAVFGKGCMAASFACAYLF----SGELFPTVIRQTGMGVVAMMARVGSVVAPLVLLLWEI 480

  Fly   531 SPALSLSAFCL-LVILGGLGTCCLVTRDKEQP 561
            ||.|..:.:.: .:|.||..|..:.|.:::.|
Frog   481 SPILPSAIYGIAAIIAGGAATFLMETNNQQLP 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4465	NP_650847.1	2A0119	67..553	CDD:273328	123/541 (23%)
CG4465	NP_650847.1	MFS	169..>303	CDD:119392	32/138 (23%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	98/422 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D704438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010