DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6300 and Acsm2

DIOPT Version :9

Sequence 1:	NP_650828.1	Gene:	CG6300 / 42351	FlyBaseID:	FBgn0038730	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001171448.1	Gene:	Acsm2 / 233799	MGIID:	2385289	Length:	600	Species:	Mus musculus

Alignment Length:	495	Identity:	103/495 - (20%)
Similarity:	196/495 - (39%)	Gaps:	73/495 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 GLLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITY-DRDTIEKIYKVTRPSIIFCDGDEFE 140
            ||.:.|.|.::.........:...|...|:.|....|.. ..|.:.::......:|:  .|||..
Mouse   127 GLHRGDRVAVVLPRIPEWWLMILGCMRTGLVFMPGTIQMRSSDILYRLQASKARAIV--AGDEVA 189

  Fly   141 KVRSATAE----LDVKIVTMRNHPLDSIKIDEVV--ATPIEENFQPAKLEKGNDQTLAILCSSGT 199
            :...|.|.    |.:|::...|.....:....::  |:.|.:     .:|..:.::.||..:|||
Mouse   190 QEVDAVAPDCSFLKIKLLVSENSREGWLNFKALLKEASTIHQ-----CVETESRESAAIYFTSGT 249

  Fly   200 TGTPKAVTITNSRHILAGNYH----------------LTTADVQYSHNTLDWITGLLTTITSGVF 248
            :|.||          :|.:.|                |:|:|:.::.:...||..:|     |.|
Mouse   250 SGPPK----------MAEHSHCSLGIKAKMDAASWTGLSTSDIIWTISDTAWIMNIL-----GAF 299

  Fly   249 STTRIIAD-------NAFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDMSSLRCYMFG 306
            ....::..       ..||....|:::..|.:...:..|....:::. .|..:.....|.....|
Mouse   300 LEPWVLGACIFVHLLPKFDSQTVLKVLSSYPINTLVGAPIIYRMLLQ-QDLSSYKFPHLHSCFSG 363

  Fly   307 GSRAALEVQKGIRSRLSHDCLQFVYGFTELGAMATINCHFDEKTGSVGQLVNGLKMKIINDDGES 371
            |.....|..:..:::...: ::.:||.||.|.:..::.....|.|.:|.......:::|::.|..
Mouse   364 GETLLPETLENWKAKTGLE-IREIYGQTETGLICRVSRTMKVKPGYLGTAFAHYDVQVIDEQGNV 427

  Fly   372 LGPDEIGEVCIMNNQHW-----SGYYGNEVETR-NMRDSLGWYHSGDLGYMDRDGFLYIMDRKKE 430
            |.|.:.|::.|.....|     |||..|..:|: |:|... |. .||.|..|.:|:.:.:.|..:
Mouse   428 LPPGKEGDIAIRVKPIWPIGMFSGYVDNPKKTQDNIRGDF-WL-MGDRGIKDPEGYFHFIGRSDD 490

  Fly   431 MLKYQNIMYYPNDIESVISEMPQVAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQD-------V 488
            ::........|:::|:.:.|.|.|:|..|........|:...|.||  |..|..:.|       :
Mouse   491 IINSSGYRIGPSEVENALMEHPAVSETAVISSPDPSRGEVVKAFVV--LAPEFLSHDRDQLTKVL 553

  Fly   489 VDYVRSRTDSKYKQLNGGAVIVDDLQRSANGKTNRMANKA 528
            .::|:|.| :.||.......:: ||.::..||..|...:|
Mouse   554 QEHVKSVT-APYKYPRKVEFVL-DLPKTVTGKIERAKLRA 591

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6300	NP_650828.1	CaiC	26..523	CDD:223395	101/488 (21%)
CG6300	NP_650828.1	AFD_class_I	47..522	CDD:302604	101/487 (21%)
Acsm2	NP_001171448.1	Acs	65..591	CDD:223442	102/493 (21%)
Acsm2	NP_001171448.1	AFD_class_I	66..594	CDD:302604	103/495 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920