Protein Alignment Acsx1L and ACSL6

DIOPT Version :10

• Sequence 1: NP_650828.1
• Gene: Acsx1L / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Alignment Length: 610
• Identity: 126/610 - (20%)
• Similarity: 199/610 - (32%)
• Gaps: 209/610 - (34%)

  Fly    56 VLTRGELLANAMRLASYMRSLGLLQ-------SDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNI 113
            |..|.|.|.:           ||||       ...:|:..:|....:.|..||:...:....|..
Human   151 VADRAEFLGS-----------GLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYD 204

  Fly   114 TYDRDTIEKIYKVTRPSIIFCDGDEFEKVRSATAELD---------VKIVTMRNHPLDS------ 163
            |.....|..|......|.:..|     |.:.|...|:         :|::.:.: |.:.
Human   205 TLGPGAIRYIINTADISTVIVD-----KPQKAVLLLEHVERKETPGLKLIILMD-PFEEALKERG 263

  Fly   164 ------IKIDEVVATPIEENFQPAKLEKGNDQTLAILC-SSGTTGTPKAVTITNSR--------- 212
                  ||..:.|....:||.|.....:.:|  |:|:| :|||||.||...:|:..
Human   264 QKCGVVIKSMQAVEDCGQENHQAPVPPQPDD--LSIVCFTSGTTGNPKGAMLTHGNVVADFSGFL 326

  Fly   213 HILAGNYHLTTADVQYSHNTL------------------------------DWITGLLTTITSGV 247
            .:....:..|.|||..|:..|                              |.:..|..||
Human   327 KVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTI---- 387

  Fly   248 FSTTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDMSSLRCYM--FGGSRA 310
            |.....:.:..:|..|:                     ..|.|         |:.::  |...|.
Human   388 FPVVPRLLNRMYDKIFS---------------------QANTP---------LKRWLLEFAAKRK 422

  Fly   311 ALEVQKGIRSRLSHD-----------------CLQFV--------------------------YG 332
            ..||:.||   :.:|                 |::.:                          ||
Human   423 QAEVRSGI---IRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYG 484

  Fly   333 FTELGAMATINCHFDEKTGSVGQLV--NGLKMKIIND------DGESLGPDEIGEVCIMNNQHWS 389
            .||..|..|.....|..:|.||..:  |.:|:..:.:      .||       ||:|:.....:.
Human   485 QTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGE-------GEICVRGPNVFK 542

  Fly   390 GYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLKYQNIMYY-PNDIESVISEMPQ 453
            ||..:...|:...||.||.|:||:|.....|.|.|:||||.:.|.....|. |..||::......
Human   543 GYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQP 607

  Fly   454 VAEVCVFGIWSNIF-------GDEAAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVD 511
            ||::.|.|.....|       ..|...:..:|.|.|....|:.      |:...|:     .|::
Human   608 VAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLC------TNKDLKK-----AILE 661

  Fly   512 DLQRSANGKTNRMAN----KAYFLH 532
            |:.|.  ||.:.:.:    ||..:|
Human   662 DMVRL--GKESGLHSFEQVKAIHIH 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1L	NP_650828.1	Firefly_Luc_like	47..522	CDD:341237	123/594 (21%)
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	126/610 (21%)