Protein Alignment Acsx1L and DIP2C

DIOPT Version :10

• Sequence 1: NP_650828.1
• Gene: Acsx1L / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_054221234.1
• Gene: DIP2C / 22982
• HGNCID: 29150
• Length: 1626
• Species: Homo sapiens
• Alignment Length: 648
• Identity: 153/648 - (23%)
• Similarity: 245/648 - (37%)
• Gaps: 182/648 - (28%)

  Fly    10 DNDQKIWSGEPVVKYFDPDLSIGEIIFHEMRRHP-QLTAQISATEGTV---LTRGELLANAMRLA 70
            ||||        .:.|   |.:.|::....:..| .:...:....|.:   ||..:|...|.::|
Human  1022 DNDQ--------ARKF---LFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIA 1075

  Fly    71 SYMRSLGLLQ-SDIVGIIGRNTTHMLAVAYACFFNGIA------FHSLNITYDRDTIEKIYKVTR 128
            ..:...|.|| .|.|.::......::|..|.|.:.|..      .|..||.....|::.|.:|:|
Human  1076 VMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR 1140

  Fly   129 PSI-----IFCDGDEFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKLEKG-N 187
            .:.     :.|   :..:.|.|.|.:||     |..||       ::.|......:||::.|. |
Human  1141 SACLMTTQLIC---KLLRSREAAAAVDV-----RTWPL-------ILDTDDLPKKRPAQICKPCN 1190

  Fly   188 DQTLAIL-CSSGTTGTPKAVTITNSRHILAGNYHLTTADVQYSHNT------------------- 232
            ..|||.| .|..|||            :|||        |:.||..
Human  1191 PDTLAYLDFSVSTTG------------MLAG--------VKMSHAATSAFCRSIKLQCELYPSRE 1235

  Fly   233 ----LDWITGL------LTTITSGVFSTTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALMI 287
                ||...||      |.::.||..|.....::...:||..|..:.:|||..|....|.|.|..
Human  1236 VAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCT 1300

  Fly   288 NCPDFET-------CDMSSLR-CYMFGGSRAALEVQKGIRSRLSHD------------------- 325
            .....:|       .|:|.:| |.:....|..:.:.:.. |:|..|
Human  1301 KGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSF-SKLFKDLGLHPRAVSTSFGCRVNLA 1364

  Fly   326 -CLQ------------------FVYGFTELGAMATINCHFDEKTGS--------VGQLVNGLKMK 363
             |||                  .||  .::.|:........|: ||        .|:::.|:::.
Human  1365 ICLQPHRLWTLAEQGTSGPDPTTVY--VDMRALRHDRVRLVER-GSPHSLPLMESGKILPGVRII 1426

  Fly   364 IINDDGES-LGPDEIGEVCIMNNQHWSGY---YGNE---VETRNMRDSLG-----WYHSGDLGYM 416
            |.|.:.:. ||...:||:.:.:..:.|||   ||:|   .:..|.|.|.|     |..:|.||::
Human  1427 IANPETKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFL 1491

  Fly   417 ----------DRDGFLYIMDRKKEMLKYQNIMYYPNDIE-SVISEMPQVAEVCVFGIWSNIFGDE 470
                      :|...||::....|.::.:.:.|:|.||| |||.....|.|..|| .|:|:.
Human  1492 RRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVF-TWTNLL--- 1552

  Fly   471 AAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVD--DLQRSANGKTNRMANKAYFL 531
              ..||:..|||.||.|:|..|.:....::..:.|..|:||  .:..::.|:..||..:..||
Human  1553 --VVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFL 1613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1L	NP_650828.1	Firefly_Luc_like	47..522	CDD:341237	141/599 (24%)
DIP2C	XP_054221234.1	DMAP_binding	<32..178	CDD:368923
		Dip2	396..972	CDD:341231
		Dip2	1048..1622	CDD:341231	145/611 (24%)