Protein Alignment Acsx1L and ACSF3

DIOPT Version :10

• Sequence 1: NP_650828.1
• Gene: Acsx1L / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_777577.2
• Gene: ACSF3 / 197322
• HGNCID: 27288
• Length: 576
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 110/532 - (20%)
• Similarity: 213/532 - (40%)
• Gaps: 84/532 - (15%)

  Fly    58 TRGELLANAMRLASYMRSL-----GLLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITYDR 117
            |..||.:.::||:..:..|     |.|:.:.|..:..|....:...:|.:.:|.....|...:..
Human    67 TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPA 131

  Fly   118 DTIEKIYKVTRPSIIFCDGDEFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAK 182
            ..:|.:...::.|::....:..|.:.....:|.|.::     ||........|..|.|   .|..
Human   132 AQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLL-----PLTPAIYTGAVEEPAE---VPVP 188

  Fly   183 LEKGNDQTLAILCSSGTTGTPKAVTIT--NSRHILAGNYH----------LTTADVQYSHNTLD- 234
            .:...::...|:.:|||||.||.|..|  |.|.::.|..|          |....:.:.|..::
Human   189 EQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNA 253

  Fly   235 -----WITGLLTTITSGVFS------------TTRIIADNAF--DPAFALRIIEEYKVTWTIQPP 280
                 |:..  |.:....||            |.||   |.|  .|....:::|.|...:| ||.
Human   254 LLCPLWVGA--TCVMMPEFSPQQVWEKFLSSETPRI---NVFMAVPTIYTKLMEYYDRHFT-QPH 312

  Fly   281 SSMALMINCPDFETCDMSSLRCYMFGGSRAALEVQKGIRSRLSHDCLQFVYGFTELG-AMATINC 344
            :...|...|.:       .:|..:.|.:...|.|.:..::...|..|: .||.||:| |::....
Human   313 AQDFLRAVCEE-------KIRLMVSGSAALPLPVLEKWKNITGHTLLE-RYGMTEIGMALSGPLT 369

  Fly   345 HFDEKTGSVGQLVNGLKMKIIND-------------DGESLG-------PDEIGEVCIMNNQHWS 389
            ......||||..:.|::::|:::             :|:..|       .::.||:.:.....:.
Human   370 TAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFR 434

  Fly   390 GYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKK-EMLKYQNIMYYPNDIESVISEMPQ 453
            .|:....||::.....||:.:||. .:.:||..:|..|.. :::|.........::|..:...|.
Human   435 EYWNKPEETKSAFTLDGWFKTGDT-VVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPS 498

  Fly   454 VAEVCVFGIWSNIFGDEAAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVDDLQRSAN 518
            :.:|.|.|:....:|....|.|..:.|..|..:::.::.|: ..:.| .:....|:|:::.|:..
Human   499 ITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARN-VLAPY-AVPSELVLVEEIPRNQM 561

  Fly   519 GKTNRMANKAYF 530
            ||.::.|...:|
Human   562 GKIDKKALIRHF 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1L	NP_650828.1	Firefly_Luc_like	47..522	CDD:341237	108/522 (21%)
ACSF3	NP_777577.2	MCS	55..571	CDD:341264	109/528 (21%)