Protein Alignment Acsx1L and ACSM6

DIOPT Version :10

• Sequence 1: NP_650828.1
• Gene: Acsx1L / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_047280594.1
• Gene: ACSM6 / 142827
• HGNCID: 31665
• Length: 520
• Species: Homo sapiens
• Alignment Length: 433
• Identity: 88/433 - (20%)
• Similarity: 152/433 - (35%)
• Gaps: 86/433 - (19%)

  Fly    78 LLQSDIVGIIGRNTTHMLAVAYACFFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCDGDEFEKV 142
            |...|.:.||...|.....:..||...||.|...:.......|....::::...|..:......|
Human   108 LSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVANEAMAPVV 172

  Fly   143 RSATAE---LDVK-IVTMRNHP--LDSIKIDEVVATPIEENFQPAKLEKGNDQTLAILCSSGTTG 201
            .||.::   |..| :|:.:::.  ||..|:.:|  .|.::.:...|    :...:||..:.||||
Human   173 NSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQV--APPKQTYMRTK----SQDPMAIFFTKGTTG 231

  Fly   202 TPKAVTITNSRHILAGNYHLTTADVQYSHNTLD-------WITGLLTTITSGVFSTTRIIAD--- 256
            .||.|..:        .|.|.....|.|...:|       |..|   ....|..|.:.::..
Human   232 APKMVEYS--------QYGLGMGFSQASRRWMDLQPTDVLWSLG---DAFGGSLSLSAVLGTWFQ 285

  Fly   257 ---------NAFDPAFALRIIEEYKVTWTIQPPSSMALMINCPDFETCDMSSLR-CYMFGG--SR 309
                     ..|.|...|.::..:.:|.....|.....::....|.:....||: |...||  |.
Human   286 GACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAAGGPISP 350

  Fly   310 AALEVQKGIRSRLSHDCLQFVYGFTELGAMATINCHFDEKTGSVGQLVNGLKMKIINDDGESLGP 374
            ..:|..|    |::...:...||.||.|.:...:.....|..|:|:.:....::|::::...|.|
Human   351 GVIEDWK----RITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSNLLPP 411

  Fly   375 DEIGEVC--IMNNQHWSGYYGNEVETRNMRDSLGWYHSGDLGYMDRDGFLYIMDRKKEMLKY--- 434
            .|.|.:.  |..||..|.|..:.|  |.....|             :.|:...:|...:::|
Human   412 GEEGNIAIRIKLNQPASLYCPHMV--RKFSSFL-------------NTFIVATNRSAIIVEYFMI 461

  Fly   435 ----------QNIMYYPNDIES-------VISEMPQVAEVCVF 460
                      ..|...|..:.|       :|..:|.:..:|.|
Human   462 CQILLSQFLILQIFESPKMLNSSTHLHSLLIKILPHLLHICTF 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1L	NP_650828.1	Firefly_Luc_like	47..522	CDD:341237	88/433 (20%)
ACSM6	XP_047280594.1	Adenylate forming domain, Class I superfamily	45..>430	CDD:473059	74/342 (22%)