Protein Alignment Acsx1L and SLC27A5

DIOPT Version :10

• Sequence 1: NP_650828.1
• Gene: Acsx1L / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_036386.1
• Gene: SLC27A5 / 10998
• HGNCID: 10999
• Length: 690
• Species: Homo sapiens
• Alignment Length: 517
• Identity: 122/517 - (23%)
• Similarity: 207/517 - (40%)
• Gaps: 120/517 - (23%)

  Fly    57 LTRGELLANAMRLASYMRS-LGLLQSDIVGIIGRNTTHML-----AVAYACFFNGIA-------- 107
            :|.|||.|.|.:.|..::: ||    |...:.....|.:|     ||...|.:.|:|
Human   143 VTFGELDARACQAAWALKAELG----DPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAW 203

  Fly   108 ----------FHS--------LNITYD-RDTIEKIYKVTRPSIIFCDGDEFEKVRSATAELDVKI 153
                      .||        |.:..| |:::|:|....:...|.|..............|...:
Human   204 INPHGRGMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAAL 268

  Fly   154 VTMRNHPLDSIKIDEVVATPIEENFQPAKLEKG---NDQTLAILCSSGTTGTPKAVTITNSRHI- 214
            ....:||:                  ||.|..|   ....|.|. :|||||.||...:|:.|.:
Human   269 DAAPSHPV------------------PADLRAGITWRSPALFIY-TSGTTGLPKPAILTHERVLQ 314

  Fly   215 ------LAGNYHLTTADVQYS----HNTLDWITGLLTTITSGVFSTTRIIADNAFDPAFALRII- 268
                  |:|   .|..||.|:    ::.:..:.|:|..:..|   .|.::|     |.|:....
Human   315 MSKMLSLSG---ATADDVVYTVLPLYHVMGLVVGILGCLDLG---ATCVLA-----PKFSTSCFW 368

  Fly   269 ---EEYKVTWTIQPPSSMALMINCPDFETCDMSSLRCYMFGGSRAALEVQKGIRSRLSHDCLQFV 330
               .::.||..:.....:..:.|.|........::|..|..|.||  :|.:..:.|.....:..|
Human   369 DDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLAMGNGLRA--DVWETFQQRFGPIRIWEV 431

  Fly   331 YGFTELGAMATINCHFDEKTGSVGQLVNGLKM----KIINDDGESLGP--DEIGEVCI------- 382
            ||.|| |.|..:|  :..:.|::|::...|:|    :::..|.|:..|  |..| .||
Human   432 YGSTE-GNMGLVN--YVGRCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQG-FCIPVGLGEP 492

  Fly   383 -------MNNQHWSGYYG-NEVE----TRNMRDSLG--WYHSGDLGYMDRDGFLYIMDRKKEMLK 433
                   ::.|.:.||.| .|:.    .||:|.| |  :|::||:..|||:||||..||..:..:
Human   493 GLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQS-GDVYYNTGDVLAMDREGFLYFRDRLGDTFR 556

  Fly   434 YQNIMYYPNDIESVISEMPQVAEVCVFGIW-SNIFGDEAAAAVVKKLGSELEAQDVVDYVRS 494
            ::......:::|.|:|::..:.:|.|:|:. ....|....|||....|...:.:.:..:||:
Human   557 WKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRA 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acsx1L	NP_650828.1	Firefly_Luc_like	47..522	CDD:341237	122/517 (24%)
SLC27A5	NP_036386.1	hsFATP2a_ACSVL_like	138..680	CDD:341261	122/517 (24%)