DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Naam and pnc-1

DIOPT Version :9

Sequence 1:	NP_001262738.1	Gene:	Naam / 42348	FlyBaseID:	FBgn0051216	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_499876.1	Gene:	pnc-1 / 176833	WormBaseID:	WBGene00021395	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	79/230 - (34%)
Similarity:	126/230 - (54%)	Gaps:	4/230 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 AFLIVDVQNDFISGSLDISNCSAQQQGHEILEPINKLLDTVDFDAVFYSLDWHPSDHVSFIDNV- 161
            |.|:||.||||:.|||.|.:..|.|:....:.|:|:||....:|.|.|:.||||.:|:||:...
Worm    94 ALLVVDFQNDFVDGSLKIGDGDAGQEPSSAITPLNELLQLSSWDLVVYTKDWHPHNHISFLSQAH 158

  Fly   162 -KMRPMDESSALDSDSAKVFDTVIFAGPPPMKQRLWPRHCVQDSWGAELHKDLKVVDHGIKVYKG 225
             ..|.|||..  ::.:...||:|.|..|...:|.|:|.||:|.|||:::|.::.:.|:...:.||
Worm   159 NSDRVMDEKD--ENKTLGFFDSVQFLKPIKTEQVLYPDHCIQKSWGSDIHPEIYIADNAEYIMKG 221

  Fly   226 TNPEVDSYSVFWDNKKLSDTTLNAQLKMKGATDIYVCGLAYDVCVGATAVDALSAGYRTILIDDC 290
            .:|.:||||.|.||...|.|.|...|:.:....:.:.|||||:||..|.:||:...:...:|.:|
Worm   222 VDPYLDSYSAFNDNNGRSKTELEDLLRRENIDAVVIAGLAYDICVRFTCLDAVKQNFLAAVIPEC 286

  Fly   291 CRGTDVHDIEHTKEKVNTSDGVIVHTNQVKAMAEG 325
            ..|.....||.::.........::..::.:.:.||
Worm   287 SAGLTKKGIEESEMAFKKQGVAMISKDEARGITEG 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naam	NP_001262738.1	EFh	20..81	CDD:238008
		EF-hand_7	21..82	CDD:290234
		nicotinamidase	97..315	CDD:238493	77/218 (35%)
pnc-1	NP_499876.1	nicotinamidase	92..310	CDD:238493	77/217 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156805
Domainoid	1	1.000	152	1.000	Domainoid score	I2644
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5938
Inparanoid	1	1.050	158	1.000	Inparanoid score	I2892
Isobase	1	0.950	-	0	Normalized mean entropy	S12195
OMA	1	1.010	-	-		QHG46475
OrthoDB	1	1.010	-	-		D1076519at2759
OrthoFinder	1	1.000	-	-		FOG0007602
OrthoInspector	1	1.000	-	-		otm14537
orthoMCL	1	0.900	-	-		OOG6_100439
Panther	1	1.100	-	-	LDO	PTHR11080
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16483
SonicParanoid	1	1.000	-	-		X6476
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890