DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nup58 and AgaP_AGAP007689

DIOPT Version :9

Sequence 1:	NP_650821.2	Gene:	Nup58 / 42342	FlyBaseID:	FBgn0038722	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	XP_308182.4	Gene:	AgaP_AGAP007689 / 1269540	VectorBaseID:	AGAP007689	Length:	429	Species:	Anopheles gambiae

Alignment Length:	389	Identity:	74/389 - (19%)
Similarity:	124/389 - (31%)	Gaps:	123/389 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 SLSSGIGSFSFPKPQATTAASLNFNTTTTTATAQPFNTGLKLGTTNATTTLGGGGIFSKPAGQAA 277
            :|..|.|...|...:|.:||....|       .:.|| |.||....|.......|:.  |.|..|
Mosquito    39 TLLRGFGFIQFHSEKAASAAIKAMN-------GKLFN-GRKLMVKVANDNRAKKGLL--PRGSTA 93

  Fly   278 APAASTFVGLGGIDVTATQPKLGDNKQDGIKIKETQVPDEI--IKTVDGLKAYIKQQKTIS---- 336
            |..|.                   :...|...::....|.|  ||     :.|..||.:::
Mosquito    94 ASNAK-------------------SNASGAAARDRSPVDPIHPIK-----RGYHPQQYSVADLSS 134

  Fly   337 ----SDIGRTSTSKFTNVSHEITNLKWALQNMATLVEGSNQQIRLMRQETVKAIQSLEMAQRTQD 397
                :.||:.......:...||..:.   :.:....||...:::       :|..|:::.....|
Mosquito   135 VYPETPIGQAPHRGIESNDCEIIVVN---KELTPYAEGIEARLK-------RAGLSVDLLFPNND 189

  Fly   398 TPAGLQFENNAPFQYFQCLVAKYEQDLIAFRQQIALTERHMHAISNPQSISPDDLKRGFRQLN-- 460
            .|.|....|.|....:.|:|...|.     :::.::|...::.|.......|.|...||...|
Mosquito   190 VPIGKVLANRASQGTYYCIVITPEN-----QERNSITVNVLYGIPAEHRNMPTDDAIGFIVKNFD 249

  Fly   461 ------------ESFISLA---------GRLH-EVHQRVEEHKE--------------------- 482
                        .::..:|         .:|| ::.||.|:|.|
Mosquito   250 DKRRQELAPHSRSAYHRVAPAVQPQPQPAQLHTDLEQRQEKHPEAIQNMINLLAANRSLTVLQYE 314

  Fly   483 ---HYLNLRR---YRLRDTTNVFERIDNPPLPTVEPQRISSGPTPFS---------NISALMNK 531
               .|||.|:   .||    .:.|.:|:....::.|..:|:.|....         .|..:|||
Mosquito   315 RLIKYLNERKETQIRL----ELGEDVDSTTASSLIPPIVSAAPVKSKQETERELQRKILDIMNK 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nup58	NP_650821.2	PHA03247	<25..195	CDD:223021
Nup58	NP_650821.2	Nucleoporin_FG2	136..>525	CDD:374260	70/381 (18%)
AgaP_AGAP007689	XP_308182.4	RRM	10..74	CDD:214636	13/42 (31%)
AgaP_AGAP007689	XP_308182.4	HGTP_anticodon	153..247	CDD:281168	20/108 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0845
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900