DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7342 and proP

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_418535.1	Gene:	proP / 948626	ECOCYCID:	EG11612	Length:	500	Species:	Escherichia coli

Alignment Length:	489	Identity:	103/489 - (21%)
Similarity:	180/489 - (36%)	Gaps:	114/489 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 YNYELY-MGYQSFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIA 145
            |.:..| :|...||.....|...|...|.  |:.|:...:|.:..|.|.|..||..||.:..:|.
E. coli    44 YGFVAYALGKVFFPGADPSVQMVAALATF--SVPFLIRPLGGLFFGMLGDKYGRQKILAITIVIM 106

  Fly   146 MTG----------NLLTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICI 200
            ...          :.:.||:..:.|.|  :|..|.:....:....|.|.||.....|..     :
E. coli   107 SISTFCIGLIPSYDTIGIWAPILLLIC--KMAQGFSVGGEYTGASIFVAEYSPDRKRGF-----M 164

  Fly   201 GFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLV---------------VPFFYLIVPESIQWLI 250
            |.:...||:|            ||:|...:.:|:               :||| :.:|..|..|.
E. coli   165 GSWLDFGSIA------------GFVLGAGVVVLISTIVGEANFLDWGWRIPFF-IALPLGIIGLY 216

  Fly   251 SKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKCSQQNQKASPHLLDLFQTPRLRRHTLILF 315
            .:...:......:.|.|:      |....|.:::.......:.|:.:...|.....|...|.:.:
E. coli   217 LRHALEETPAFQQHVDKL------EQGDREGLQDGPKVSFKEIATKYWRSLLTCIGLVIATNVTY 275

  Fly   316 FKSMVITLCYDAVSRNV---QGLGISPFVMFSLSATAILPACLLIIALQDRIGRK---AMASASL 374
            :  |::|.....:|.|:   :..|:...:...:....:.|...|   |.||.||:   .:.|.:|
E. coli   276 Y--MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGL---LSDRFGRRPFVLLGSVAL 335

  Fly   375 LLSGI--FISVTG---GIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQ 434
            .:..|  ||.:..   |:|||.        ||:...::..|...:|....|.:     ||.:|..
E. coli   336 FVLAIPAFILINSNVIGLIFAG--------LLMLAVILNCFTGVMASTLPAMF-----PTHIRYS 387

  Fly   435 GVAA-----VHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSL 494
            .:||     |.|||...|..:..:..::::.  :|...|.|::::|....:.:.||.:|.
E. coli   388 ALAAAFNISVLVAGLTPTLAAWLVESSQNLM--MPAYYLMVVAVVGLITGVTMKETANRP----- 445

  Fly   495 EDGENFGKNDRWYTFSFLEGRTQSAATLDTQNAK 528
                             |:|.|.:|:  |.|.||
E. coli   446 -----------------LKGATPAAS--DIQEAK 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	95/450 (21%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	38/174 (22%)
proP	NP_418535.1	PRK10642	10..499	CDD:182611	103/489 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
	1	1.000