Protein Alignment CG7342 and SLC22A4

DIOPT Version :9

• Sequence 1: NP_001247196.1
• Gene: CG7342 / 42335
• FlyBaseID: FBgn0038716
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_003050.2
• Gene: SLC22A4 / 6583
• HGNCID: 10968
• Length: 551
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 148/570 - (25%)
• Similarity: 268/570 - (47%)
• Gaps: 65/570 - (11%)

  Fly     1 MLEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPKYWCADGLPASIESPVDSS 65
            |.:.|:::...|::...|.::..|.....:.:..:..|...::..|::.|.....|::.|...::
Human     1 MRDYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCRVPDAANLSSAWRNN 65

  Fly    66 CLPL----NRNISTPNTC-----------------------------------YSYNYELYMGYQ 91
            .:||    .|.:  |::|                                   :.::.::|:  .
Human    66 SVPLRLRDGREV--PHSCSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYL--S 126

  Fly    92 SFPSEMDWVCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTG-NLLTIWS 155
            :..:|.:.||.|.||:.|..|:||||.::||.|.|.|:|..||..:|. |.:...|| :.|.|:|
Human   127 TVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGRKNVLF-ATMAVQTGFSFLQIFS 190

  Fly   156 TNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRS 220
            .:..:|.:..:|.|:...||:|:.:||..|.:..|||.:..::.:..|:.:|.|..|..|..:|.
Human   191 ISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRD 255

  Fly   221 WRGFLLTTSLP-LLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEE 284
            ||..||..::| :|.||.::.| |||.:||||::::..|...:::.||:|...|....: :.:||
Human   256 WRMLLLALTVPGVLCVPLWWFI-PESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIF-DSVEE 318

  Fly   285 CKCSQQNQKASPHLLDLFQTPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATA 349
            ....:| |||  .:||||:|..:...|::.....|:.::.|.|:|.:...|....::...|||..
Human   319 LNPLKQ-QKA--FILDLFRTRNIAIMTIMSLLLWMLTSVGYFALSLDAPNLHGDAYLNCFLSALI 380

  Fly   350 ILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTV 414
            .:||.:....|...:.|:.:.:|.|...|      |.::|..........|.:.|.::|:||:|.
Human   381 EIPAYITAWLLLRTLPRRYIIAAVLFWGG------GVLLFIQLVPVDYYFLSIGLVMLGKFGITS 439

  Fly   415 AYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLC 479
            |::....:..||.||.||...|.....|....:..:.|.::..:....||.|::|.|::|...|.
Human   440 AFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIAPYFVYLGAYNRMLPYIVMGSLTVLIGILT 504

  Fly   480 LLLPETLHRTLPTSLEDGENFGKNDRWYTFSFLEGRTQSAATLDTQNAKM 529
            |..||:|..|||.:||..:..    :|    |..|:....:....:|.|:
Human   505 LFFPESLGMTLPETLEQMQKV----KW----FRSGKKTRDSMETEENPKV 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	137/519 (26%)
		MFS	93..>243	CDD:119392	54/151 (36%)
SLC22A4	NP_003050.2	2A0119	12..518	CDD:273328	139/521 (27%)
		MFS	123..508	CDD:119392	120/398 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153710
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950