DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7342 and Slc22a15

DIOPT Version :9

Sequence 1:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001101177.1	Gene:	Slc22a15 / 310732	RGDID:	1311184	Length:	548	Species:	Rattus norvegicus

Alignment Length:	565	Identity:	143/565 - (25%)
Similarity:	234/565 - (41%)	Gaps:	65/565 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEVDKILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQT------IISFVPKY-W-CADGLPASI 58
            :||::..:..|:....||.:..|..|:     |..|..|      :|...|.| | .|:.||...
  Rat     1 MEVEEAFQAVGEMGLYQMYLCFLLAVL-----LQLYVATEAILIALIGATPAYHWDMAELLPNQS 60

  Fly    59 ESPVDSS--------CLPLNRNISTPNTCYSYNYELYMGYQSFPSEMDWVCADAWKLTLGQSMFF 115
            .|...|.        .|..|.:....:..:|.:      :.|..||...:...::|::...|.||
  Rat    61 HSNQSSGKGQAFGDWLLTANGSEIHKHVHFSNS------FTSIASEWFLIANRSYKVSAASSFFF 119

  Fly   116 VGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSNFVMMY 180
            .|..||.:..|.|:|..||..:.:....:.:...:...:|.:...|.:.|.:.|:......::.:
  Rat   120 SGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAF 184

  Fly   181 ILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYLIVPES 245
            :|:.|.:..:...|..||. |.|:.:|......:...:||||...:..:|...||....|.:|||
  Rat   185 VLLNECVGAAYWALAGSIG-GLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPES 248

  Fly   246 IQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIEECKC-------SQQNQKASPHLLDLFQ 303
            .:||.|:.:...|...|..:||.|             .:.||       :.::.:.:...||||:
  Rat   249 PRWLYSQGRLSEAEEALYLIAKRN-------------RKLKCTFSLTHPANRSYRETGSFLDLFR 300

  Fly   304 TPRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIAL--QDRIGR 366
            ...|..|||||.|...|.:|.|..::.:...||.|.:...:||....:|:..|.|.|  |...||
  Rat   301 YRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQRWFGR 365

  Fly   367 KAMASASLLLSGIFISVTGGIIFAASASDKTTTLLV---SLSVVGRFGVTVAYNSGAQYATELIP 428
            |...:|.|.|.|:...:   ::|.....|.....:|   |||::|:..::.|:|....|.:||.|
  Rat   366 KRTLAAFLCLGGLACLI---VMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYP 427

  Fly   429 TCVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTS 493
            |.:|..|:....:........:.::...:.|...||.|:.|...|....|.|||||||:..|..:
  Rat   428 TVIRNVGLGTCSMFSRVGGIIAPFVPSLKDVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLET 492

  Fly   494 LEDGENFGKNDRWYTFSFLEGRTQSAATLDTQN--AKMYSQSTES 536
            ..|.:       .|::..|.....|..|||...  .|..|..:||
  Rat   493 FSDLQ-------MYSYRRLGEEALSLQTLDPPQPLGKASSLGSES 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	129/506 (25%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	34/149 (23%)
Slc22a15	NP_001101177.1	MFS	111..469	CDD:119392	95/374 (25%)
Slc22a15	NP_001101177.1	MFS_1	111..450	CDD:284993	91/355 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347226
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940