DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5316 and HNT3

DIOPT Version :9

Sequence 1:	NP_650805.1	Gene:	CG5316 / 42322	FlyBaseID:	FBgn0038704	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_014901.1	Gene:	HNT3 / 854432	SGDID:	S000005784	Length:	217	Species:	Saccharomyces cerevisiae

Alignment Length:	229	Identity:	65/229 - (28%)
Similarity:	94/229 - (41%)	Gaps:	79/229 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSWSSALIKDISKPENL------IISSEIAVVIADKFPKAQHHYLVLPLADIPSIFHLNRSHLS- 58
            |||..||...::.||.:      ....::: :|.|.|||::.|.|:|     |....|:|||.:
Yeast     1 MSWRYALKNYVTSPETVNDDTVTYFDDKVS-IIRDSFPKSECHLLIL-----PRTMQLSRSHPTK 59

  Fly    59 --------------------------------------------LLEELHLLARNVVEVKGVRWQ 79
                                                        :|::.:...||.|:
Yeast    60 VIDAKFKNEFESYVNSAIDHIFRHFQEKFRIKKSDDDKDPCWDDILKDKNKFVRNFVQ------- 117

  Fly    80 DFNVGFHAEPSMQRLHLHVISKDFVSTSLKTKKHWNSFNTELFVPYTKLYAQLEKENSISRLPKS 144
               ||.|:.|||..||:|||||||.|..||.|||:|||||..|:.:..|  .|..:|  ....|.
Yeast   118 ---VGIHSVPSMANLHIHVISKDFHSVRLKNKKHYNSFNTGFFISWDDL--PLNGKN--LGTDKE 175

  Fly   145 LKDELLAK-PLICNQCEFVARNLPS----LKGHL 173
            ::...|.: .|:|..|:   ||..:    ||.||
Yeast   176 IETTYLKEHDLLCCYCQ---RNFSNKFSLLKKHL 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5316	NP_650805.1	DcpS_C	8..100	CDD:288796	29/142 (20%)
		zf-C2HE	119..179	CDD:292895	16/60 (27%)
		DcpS_C	235..326	CDD:288796
		zf-C2HE	345..405	CDD:292895
HNT3	NP_014901.1	HIT	15..139	CDD:395984	32/139 (23%)
HNT3	NP_014901.1	zf-C2HE	153..212	CDD:406643	17/61 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345731
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0562
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1	Normalized mean entropy	S3909
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003607
OrthoInspector	1	1.000	-	-		oto99583
orthoMCL	1	0.900	-	-		OOG6_103324
Panther	1	1.100	-	-	LDO	PTHR12486
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R76
SonicParanoid	1	1.000	-	-		X4024
TreeFam	0	0.000	Not matched by this tool.
	10	9.720