Protein Alignment: CG5316 and Aptx

• Sequence 1: NP_650805.1
• Gene: CG5316
• FlyBaseID: FBgn0038704
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: NP_079821.3
• Gene: Aptx
• MGIID: 1913658
• Length: 342
• Species: Mus musculus
• Alignment Length: 178
• Identity: 72/179 (40%)
• Similarity: 104/179 (58%)
• Gaps: 9/179 (5%)

  Fly     3 WSSALIKDISKPENLIISSEIAVVIADKFPKAQHHYLVLPLADIPSIFHLNRSHLSLLEELHLLA 67
            ||..|...:..|:..:...:..|||.||:|||:||:||||.|.|.|:..:...||.||:.:|.:.
Mouse   167 WSQGLKMSMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVG 231

  Fly    68 RNVV-EVKGVRWQDFNVGFHAEPSMQRLHLHVISKDFVSTSLKTKKHWNSFNTELFVPYTKLYAQ 131
            ..|: :..|.....|.:|:||.|||..:||||||:||.|..||.||||||||||.|:....:...
Mouse   232 EKVIADFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKM 296

  Fly   132 LEKENSISRLPKSLKD---ELLAKPLICNQCEFVARNLPSLKGHLVGH 176
            :::...:     ::||   |||..||.|::|:.:..::|.||.||..|
Mouse   297 VQEAGRV-----TVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKH 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5316	NP_650805.1	DcpS_C	8..100	CDD:288796	37/93 (40%)
		zf-C2HE	119..179	CDD:292895	18/62 (29%)
		DcpS_C	235..326	CDD:288796
		zf-C2HE	345..405	CDD:292895
Aptx	NP_079821.3	Interactions with ADPRT and NCL. {ECO:0000250}	1..102
		FHA	12..105	CDD:238017
		Nuclear localization signal. {ECO:0000250}	118..122
		aprataxin_related	164..265	CDD:238609	40/98 (41%)
		Interaction with DNA substrate. {ECO:0000250|UniProtKB:Q7Z2E3}	193..197		3/4 (75%)
		Interaction with DNA substrate. {ECO:0000250|UniProtKB:Q7Z2E3}	255..256		1/1 (100%)
		Histidine triad motif. {ECO:0000255|PROSITE-ProRule:PRU00464}	258..262		2/4 (50%)
		zf-C2HE	284..340	CDD:292895	18/62 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C198584060
eggNOG	1	0.900				E1_KOG0562
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950		1	Normalized mean entropy	S3909
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0005179
OrthoInspector	1	1.000				T1083386
orthoMCL	1	0.900				OOG5_129343
Panther	1	1.100			LDO	PTHR12486
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R76
TreeFam	0	0.000	Not matched by this tool.
	9	8.720