| Sequence 1: | NP_650805.1 | Gene: | Aptx / 42322 | FlyBaseID: | FBgn0038704 | Length: | 662 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_079821.3 | Gene: | Aptx / 66408 | MGIID: | 1913658 | Length: | 342 | Species: | Mus musculus |
| Alignment Length: | 178 | Identity: | 72/178 - (40%) |
|---|---|---|---|
| Similarity: | 104/178 - (58%) | Gaps: | 9/178 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3 WSSALIKDISKPENLIISSEIAVVIADKFPKAQHHYLVLPLADIPSIFHLNRSHLSLLEELHLLA 67
Fly 68 RNVV-EVKGVRWQDFNVGFHAEPSMQRLHLHVISKDFVSTSLKTKKHWNSFNTELFVPYTKLYAQ 131
Fly 132 LEKENSISRLPKSLKD---ELLAKPLICNQCEFVARNLPSLKGHLVGH 176 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Aptx | NP_650805.1 | DcpS_C | 8..113 | CDD:463415 | 44/105 (42%) |
| zf-C2HE | 118..179 | CDD:465082 | 19/62 (31%) | ||
| DcpS_C | 235..339 | CDD:463415 | |||
| zf-C2HE | 344..406 | CDD:465082 | |||
| KLF1_2_4_N | <511..585 | CDD:425360 | |||
| Aptx | NP_079821.3 | Interactions with ADPRT/PARP1 and NCL. /evidence=ECO:0000250 | 1..102 | ||
| FHA_APTX | 9..108 | CDD:438787 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 114..170 | 2/2 (100%) | |||
| Nuclear localization signal. /evidence=ECO:0000250 | 118..122 | ||||
| aprataxin_related | 164..265 | CDD:238609 | 40/98 (41%) | ||
| Interaction with DNA substrate. /evidence=ECO:0000250|UniProtKB:Q7Z2E3 | 193..197 | 2/3 (67%) |