DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5316 and Aptx

DIOPT Version :9

Sequence 1:NP_650805.1 Gene:CG5316 / 42322 FlyBaseID:FBgn0038704 Length:662 Species:Drosophila melanogaster
Sequence 2:NP_079821.3 Gene:Aptx / 66408 MGIID:1913658 Length:342 Species:Mus musculus


Alignment Length:178 Identity:72/178 - (40%)
Similarity:104/178 - (58%) Gaps:9/178 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 WSSALIKDISKPENLIISSEIAVVIADKFPKAQHHYLVLPLADIPSIFHLNRSHLSLLEELHLLA 67
            ||..|...:..|:..:...:..|||.||:|||:||:||||.|.|.|:..:...||.||:.:|.:.
Mouse   167 WSQGLKMSMKDPKMQVYKDDQVVVIKDKYPKARHHWLVLPWASISSLKVVTSEHLELLKHMHAVG 231

  Fly    68 RNVV-EVKGVRWQDFNVGFHAEPSMQRLHLHVISKDFVSTSLKTKKHWNSFNTELFVPYTKLYAQ 131
            ..|: :..|.....|.:|:||.|||..:||||||:||.|..||.||||||||||.|:....:...
Mouse   232 EKVIADFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEYFLESQAVIKM 296

  Fly   132 LEKENSISRLPKSLKD---ELLAKPLICNQCEFVARNLPSLKGHLVGH 176
            :::...:     ::||   |||..||.|::|:.:..::|.||.||..|
Mouse   297 VQEAGRV-----TVKDGTCELLKLPLRCHECQQLLPSIPQLKEHLRKH 339

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG5316NP_650805.1 DcpS_C 8..100 CDD:288796 36/92 (39%)
zf-C2HE 119..179 CDD:292895 18/61 (30%)
DcpS_C 235..326 CDD:288796
zf-C2HE 345..405 CDD:292895
AptxNP_079821.3 Interactions with ADPRT/PARP1 and NCL. /evidence=ECO:0000250 1..102
FHA 12..105 CDD:238017
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..170 2/2 (100%)
Nuclear localization signal. /evidence=ECO:0000250 118..122
aprataxin_related 164..265 CDD:238609 39/97 (40%)
Interaction with DNA substrate. /evidence=ECO:0000250|UniProtKB:Q7Z2E3 193..197 2/3 (67%)