DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5316 and SPCC18.09c

DIOPT Version :9

Sequence 1:	NP_650805.1	Gene:	CG5316 / 42322	FlyBaseID:	FBgn0038704	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	NP_588388.1	Gene:	SPCC18.09c / 2539198	PomBaseID:	SPCC18.09c	Length:	232	Species:	Schizosaccharomyces pombe

Alignment Length:	202	Identity:	62/202 - (30%)
Similarity:	91/202 - (45%)	Gaps:	42/202 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ISKPE---NLIISSEIAVVIADKFPKAQHHYLVLPLADIPSIFHLN-----RSHLSLLEELHLLA 67
            |..||   |:|...:..|::.|.|||::.| |:|...| |.:.|::     ..|.||:|:|....
pombe    42 IESPESYKNVIYYDDDVVLVRDMFPKSKMH-LLLMTRD-PHLTHVHPLEIMMKHRSLVEKLVSYV 104

  Fly    68 RNVVEVKGVRWQD-----------------FNVGFHAEPSMQRLHLHVISKDFVSTSLKTKKHWN 115
            :.  ::.|:.:.:                 ..|||||.|||..||||:::.|.||.|||...|:.
pombe   105 QG--DLSGLIFDEARNCLSQQLTNEALCNYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYI 167

  Fly   116 SFNTELFVPYTKLYAQLEKENSISRLP-KSLKDELLAKPLICNQC-EFVARNLPSLKGHLVGHLQ 178
            ||.:..||         :.:...|.|| :.....|..:.|.|.:| |...|:...||.||.....
pombe   168 SFTSPFFV---------KIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYD 223

  Fly   179 D--PKSV 183
            |  .|||
pombe   224 DWLDKSV 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5316	NP_650805.1	DcpS_C	8..100	CDD:288796	34/113 (30%)
		zf-C2HE	119..179	CDD:292895	15/61 (25%)
		DcpS_C	235..326	CDD:288796
		zf-C2HE	345..405	CDD:292895
SPCC18.09c	NP_588388.1	HIT	45..156	CDD:279559	34/114 (30%)
SPCC18.09c	NP_588388.1	zf-C2HE	172..224	CDD:292895	15/60 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0562
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003607
OrthoInspector	1	1.000	-	-		oto101212
orthoMCL	1	0.900	-	-		OOG6_103324
Panther	1	1.100	-	-	LDO	PTHR12486
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R76
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.840