Protein Alignment CG18493 and PRCP

DIOPT Version :10

• Sequence 1: NP_650803.1
• Gene: CG18493 / 42319
• FlyBaseID: FBgn0038701
• Length: 480
• Species: Drosophila melanogaster
• Sequence 2: NP_955450.2
• Gene: PRCP / 5547
• HGNCID: 9344
• Length: 517
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 128/531 - (24%)
• Similarity: 208/531 - (39%)
• Gaps: 114/531 - (21%)

  Fly    14 AIGLVQSLDIPK--------IKDVPLLVKTLKNLNRGPPHQVVTKRANVQEKWITQKLDNFNASN 70
            |:..:.||.:|.        .|:..:|....|.|..|..|..:.:..:.:    |..:|:|..:.
Human    25 ALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKALAAGQLHICIIQLNHYK----TPLVDHFGFNT 85

  Fly    71 TQTYQMRYLLNDEF-QTEGSPIFIYLGGEWEIEESMVSAGHWYDMAQEHNGVLVYTEHRYYGQSI 134
            .:|:..|||:.|:: :..|..|..|.|.|.:|.....:.|..:|:|:|...:||:.||||||:|:
Human    86 VKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESL 150

  Fly   135 PTSTMSTED---LKYLDVKQALADVAVFIETFKAENPQLANSKVILAGGSYSATMVVWFKRLYPD 196
            |....|.:|   |.:|..:|||||.|..|:..|...|...|..||..||||...:..||:..||.
Human   151 PFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPH 215

  Fly   197 LIVGGWASSAPILAKVDFTE---YKEVVGQAFLQLGGQKCYDRIENGIAELESMFANKRGAE-AR 257
            ::||..|:||||....|...   :.::|...| :..|..|.:.|......:..:.....|.: ..
Human   216 MVVGALAASAPIWQFEDLVPCGVFMKIVTTDF-RKSGPHCSESIHRSWDAINRLSNTGSGLQWLT 279

  Fly   258 AMLRLCNSFDDQNDLDLWTLFSSISNIFAGVA-----------QYQGTGDIEYYCDYLLSFN-DD 310
            ..|.||:....|   |:..|...||..:..:|           |......|:..|.||.:.| .|
Human   280 GALHLCSPLTSQ---DIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSD 341

  Fly   311 ATAIANF-----VYWAW-GMGNCIDARYEGSVEYYLWGVDHFDASRPWYYQTCNE---------- 359
            :..:.|.     ||:.: |...|::.....:......|         |.||.|.|
Human   342 SLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLG---------WSYQACTEVVMPFCTNGV 397

  Fly   360 ------YGW---------YQSSGSRNQPFGTKFPATLYINLCGDVFSSQYGNEQINNNAASTNEY 409
                  :.|         :|..|.|.:|               ...::.||.:.|:::.
Human   398 DDMFEPHSWNLKELSDDCFQQWGVRPRP---------------SWITTMYGGKNISSHT------ 441

  Fly   410 FGGMEPGVDNIYMTHGELDPWNPMGHGVEQG------ATVIANASHCSDFGSIKSTDSDEMRASK 468
                     ||..::||||||:  |.||.:.      |..|:..:|..|..:..:.|...:..::
Human   442 ---------NIVFSNGELDPWS--GGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLAR 495

  Fly   469 EKLAELVRQWL 479
            ......::.|:
Human   496 SLEVRHMKNWI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18493	NP_650803.1	alpha/beta hydrolases	61..471	CDD:473884	116/466 (25%)
PRCP	NP_955450.2	alpha/beta hydrolases	78..498	CDD:473884	116/464 (25%)