Protein Alignment CG5555 and brap

DIOPT Version :10

• Sequence 1: NP_001262724.1
• Gene: CG5555 / 42302
• FlyBaseID: FBgn0038686
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001002466.1
• Gene: brap / 436739
• ZFINID: ZDB-GENE-040718-168
• Length: 578
• Species: Danio rerio
• Alignment Length: 604
• Identity: 239/604 - (39%)
• Similarity: 354/604 - (58%)
• Gaps: 81/604 - (13%)

  Fly     7 NISLCVIKIETDLDPSADSEG----AVS--AEHPTNPRVL----------KERERDR------GL 49
            ::||.||::|. .|.|...:|    |||  :|.....:.|          .:.||..      |.
Zfish     2 SVSLVVIRLEL-ADQSDSPQGFHYCAVSEMSEDEMREKALGSAKATLGGKTDLERGAILHQHLGS 65

  Fly    50 RQSRDITIETYTNQRWKRELSEPRQQEMNWVAAVQHVNSPSAGS--SREITPRSGDDGQAGASAS 112
            |...|:.|||:                           .||.|:  .:|:.....|......|.|
Zfish    66 RVMSDMVIETF---------------------------QPSTGAEEGKEVDVSQTDVNMTPDSPS 103

  Fly   113 -NFPQEIGYFSGNPIVEVTKGLIHLYKKNERKAIKE--APSNQLCLLAVPATLNCHDLLNFIAPC 174
             ..|.:|.:|||||.||:..|::||||.|:..::.|  ..|..||:|.||.|:..|||:.|:||.
Zfish   104 KQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLTEDVRRSAMLCILTVPTTMTSHDLMKFVAPY 168

  Fly   175 HAEIKHIQIVRDGSPNQFMVLLEFRSNESALEFYKSYNGSTYNSLEPDSLCHAVWV--SEVERSE 237
            :..::|::|:||.:|||:|||::|||...|..||.:.||..:||:| |::|..|:|  :||.:||
Zfish   169 NDVMEHMKIIRDSTPNQYMVLVKFRSQADADSFYTTRNGRQFNSIE-DAVCQLVYVERAEVIKSE 232

  Fly   238 HGA--PPMGHTELPTCPVCLERMDESVDGVLTILCNHAFHASCLMKWGDSTCPVCRHVQTPGLVE 300
            .||  |.|..||||.|.||||||||||:||||.||||:||:.||.:|.|::|||||:.|||..||
Zfish   233 EGASLPVMDLTELPKCTVCLERMDESVNGVLTTLCNHSFHSQCLQRWEDASCPVCRYCQTPEPVE 297

  Fly   301 DSVCMECEGTDSLWICLICGHVGCGRYQGGHAAAHFRATNHTFAMQLGTSSVWDYAGDNFVHRLF 365
            ::.|.||...::|||||||||:|||||...||..||..|.||:||||....||||||||:||||.
Zfish   298 ENKCFECGVQENLWICLICGHIGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLV 362

  Fly   366 QNKSDGKLVASQTEKDE-REEKIDSMQMEFTYLLTSQLDTQRKYYEERMERLE----QEWQNHKA 425
            .:|:|||:|..:.|.|. ::||||::|:|::|||||||::||.|:|.::..||    :|..|.||
Zfish   363 ASKTDGKMVQYECEGDTCQDEKIDALQLEYSYLLTSQLESQRIYWENKIVHLEKDTAEEINNMKA 427

  Fly   426 TANDAKTEVSELQQLQQNMQKEKVNLERKLAQHTAKLKDVQKQLNEERELSKALQSNQSSWHGKY 490
            ...:...:...|::....:.|:|.::::|.:|...|:..:.::|.||:|:::.|::|||....:.
Zfish   428 KFKETIDKCDSLERKLNELAKDKQSIDKKCSQLNNKVAKLSQELREEQEMNRCLRANQSQLQAQL 492

  Fly   491 KLLEQQYNEFKQTHDAEVTELKEQLRDIMFFLDNQQKL----ANT--EIAGGTV---TGIAEKEP 546
            :..|::..:.....|.::.||:|||||:||:|:.||::    |:|  ||..|.:   :..|..:|
Zfish   493 QEEERRVQDTAANKDDQIAELQEQLRDVMFYLETQQQIDRMPADTRQEIQEGQINIASAPAAPQP 557

  Fly   547 DPN-------TRRRNRRKK 558
            .|:       |.|:.|.|:
Zfish   558 GPSAHGSGKMTGRKGRSKR 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5555	NP_001262724.1	RRM_BRAP2	150..234	CDD:410117	39/85 (46%)
		RING-H2_BRAP2	249..292	CDD:438121	30/42 (71%)
		zf-UBP	304..366	CDD:460464	40/61 (66%)
		SMC_prok_B	<367..>519	CDD:274008	53/156 (34%)
brap	NP_001002466.1	RRM_BRAP2	144..227	CDD:410117	38/83 (46%)
		RING-H2_BRAP2	246..289	CDD:438121	30/42 (71%)
		zf-UBP	301..363	CDD:460464	40/61 (66%)
		COG4372	416..>543	CDD:443500	36/126 (29%)