Protein Alignment ChT and Slc5a2

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_072112.2
• Gene: Slc5a2 / 64522
• RGDID: 620217
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 132/540 - (24%)
• Similarity: 215/540 - (39%)
• Gaps: 153/540 - (28%)

  Fly     3 NIAGVVSIVLFYLLILVVGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGT 67
            |.|.::.|..::||::.||:|:..:...|  :.....|||||:..:....::.|:.:|.|:..|.
  Rat    20 NPADILVIAAYFLLVIGVGLWSMFRTNRG--TVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGL 82

  Fly    68 AEAIYTSGLVWCQAPFGYALSLVFG----GIFFANPMRKQGYITMLDPLQDSFGERMGGL----- 123
            |.....|||    |..|:..:.:|.    |..|.......|.|||...|:..||.|...|
  Rat    83 AGTGAASGL----AVAGFEWNALFVVLLLGWLFVPVYLTAGVITMPQYLRKRFGGRRIRLYLSVL 143

  Fly   124 -LFL--------PALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVA 179
             |||        ....|.||    |..|||..:        ..|||....|.:.||:.|||.::.
  Rat   144 SLFLYIFTKISVDMFSGAVF----IQQALGWNI--------YASVIALLGITMIYTVTGGLAALM 196

  Fly   180 YTDVIQLFCIFIGLWMCIPFAWS---------NEHVGSLSDLEVD---WIGHV-----EPKKHWL 227
            |||.:|.|.|..|.::...:|:.         ::::|:::.|.|.   .:|::     :|:..
  Rat   197 YTDTVQTFVILAGAFILTGYAFHEVGGYSGLFDKYLGAVTSLTVSKDPAVGNISSTCYQPRPD-- 259

  Fly   228 YIDYGLLL--VFGGIPW------------------QVYFQRVLSSKTAGRAQLLSYVAAAGCIL- 271
              .|.||.  |.|.:||                  ||..||.|:.|.      |::: .|||||
  Rat   260 --SYHLLRDPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKN------LTHI-KAGCILC 315

  Fly   272 --MAIPP----VLIGAIAKATPWNETDYKGPYPLTVDETSMILPMV-------------LQY--- 314
              :.:.|    |:.|.|::..          ||   ||.:.::|.|             :.|
  Rat   316 GYLKLMPMFLMVMPGMISRIL----------YP---DEVACVVPEVCKRVCGTEVGCSNIAYPRL 367

  Fly   315 ---LTPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEI-----IWVMRV 371
               |.|:.:....|..:.||:|||..|...|::::|..::|..: |.:|.:.|:     :||:.:
  Rat   368 VVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRL-RPRAGDRELLLVGRLWVVFI 431

  Fly   372 AIIVVGILATIMALT-------IPSIYGLWSMCSDLVYVILFPQLLMVVHFKKHCNTYGSLSAYI 429
            ..:.|..|..:.|..       |.|:....:.....|:|:..        |....|..|:....|
  Rat   432 VAVSVAWLPVVQAAQGGQLFDYIQSVSSYLAPPVSAVFVLAL--------FVPRVNEKGAFWGLI 488

  Fly   430 VALAIRLSGGEAILGLAPLI 449
                     |..::|||.||
  Rat   489 ---------GGLLMGLARLI 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	130/536 (24%)
Slc5a2	NP_072112.2	SLC5-6-like_sbd	22..670	CDD:444915	131/538 (24%)