Protein Alignment ChT and Slc5a7

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_071308.2
• Gene: Slc5a7 / 63993
• MGIID: 1927126
• Length: 580
• Species: Mus musculus
• Alignment Length: 516
• Identity: 305/516 - (59%)
• Similarity: 385/516 - (74%)
• Gaps: 15/516 - (2%)

  Fly     3 NIAGVVSIVLFYLLILVVGIWAGRK-KQSGNDSE--EEVMLAGRSIGLFVGIFTMTATWVGGGYI 64
            ::.|:|:|:||||||.:|||||..| |.|||..|  |.:::.||.|||.||.|||||||||||||
Mouse     4 HVEGLVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYI 68

  Fly    65 NGTAEAIY--TSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGGLLFLP 127
            ||||||:|  ..||.|.|||.||:|||:.||:|||.|||.:||:|||||.|..:|:|||||||:|
Mouse    69 NGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIP 133

  Fly   128 ALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIG 192
            ||.||:||||.|.:|||||:|||||:|...|||:|:.|||.|||.|||||||||||:||||||||
Mouse   134 ALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIG 198

  Fly   193 LWMCIPFAWSNEHVGSL------SDLEVDWIGHVEPKKHWLYIDYGLLLVFGGIPWQVYFQRVLS 251
            ||:.:|||.|:..|..:      :..:..|:|.:|..:.:.::|..|||:.||||||.|||||||
Mouse   199 LWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLS 263

  Fly   252 SKTAGRAQLLSYVAAAGCILMAIPPVLIGAIAKATPWNETDYKGPYPLTVDETSMILPMVLQYLT 316
            |.:|..||:||::||.||::||:|.:.||||..:|.||:|.|..|.|.|.:|..||||:|||||.
Mouse   264 SSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILPIVLQYLC 328

  Fly   317 PDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVGILAT 381
            |.::|||||||||||||||||||:|||:||||||:|:|.|||.||:.||:||||:.::|.|..||
Mouse   329 PVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVLVFGASAT 393

  Fly   382 IMALTIPSIYGLWSMCSDLVYVILFPQLLMVVHFKKHCNTYGSLSAYIVALAIRLSGGEAILGLA 446
            .|||...::||||.:.|||||:|:|||||.|: |.|..||||:::.||..|.:|::|||..|.|.
Mouse   394 AMALLTKTVYGLWYLSSDLVYIIIFPQLLCVL-FIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQ 457

  Fly   447 PLIKYPGYDEETK---EQMFPFRTMAMLLSLVTLISVSWWTKMMFESGKLPPSYDYFRCVV 504
            |||.||||..:..   .|.|||:|::|:.|..|.|.||:..|.:||||.|||..|.|..||
Mouse   458 PLIFYPGYYSDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDVFDAVV 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	290/487 (60%)
Slc5a7	NP_071308.2	SLC5sbd_CHT	8..495	CDD:271368	290/487 (60%)
		Mediates interaction with SEC14L1. /evidence=ECO:0000250|UniProtKB:Q9JMD7	502..580		11/17 (65%)
		Dileucine-like motif. /evidence=ECO:0000250|UniProtKB:Q9GZV3	527..532