Protein Alignment ChT and Slc5a8

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001178916.1
• Gene: Slc5a8 / 500820
• RGDID: 1564146
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 115/551 - (20%)
• Similarity: 221/551 - (40%)
• Gaps: 97/551 - (17%)

  Fly    11 VLFYLLILV---VGIW---AGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTAE 69
            |:|..::|:   :||:   ||    .|..:.::.::.|||:.......::||:::....:.||..
  Rat    16 VVFAGMLLISAAIGIYYAFAG----GGQQTSKDFLMGGRSMSAVPVALSLTASFMSAVTVLGTPA 76

  Fly    70 AIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGGLLFLPALCGEV- 133
            .:|..|.::......|...:|.....|.....:.|..:..:.|:..|..      |: .|||.|
  Rat    77 EVYRFGAIFSIFGVTYFFVVVISAEVFLPVFYRLGITSTYEYLELRFNR------FI-RLCGTVL 134

  Fly   134 ------FWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIG 192
                  .:...::.|....|:.:...|...:|:.:..:..||...|||.:|.:|||.|:..:..|
  Rat   135 FIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVVWTDVFQVGIMVAG 199

  Fly   193 LWMCIPFAWSNEHVGSLSDLEVD---------WIGHVEP-KKHWLYIDYGLLLVFGGIPW----- 242
            ....|..|...:  |.::.:..|         |..:..| ::|    .:..::|.|...|
  Rat   200 FASVIIQASITQ--GGINTILSDASNGGRLNFWNFNPNPLQRH----TFWTIIVGGTFTWTTIYG 258

  Fly   243 --QVYFQRVLSSKTAGRAQLLSYVAAAGCILMAIPPVLIGAIAKATPWNETDYKGPYPLT---VD 302
              |...||.:|.|:...|:|..||...|..::.|..|..| :|..:.:::.|     |.|   |.
  Rat   259 VNQSQVQRYISCKSRLHAKLSLYVNLVGLWVILICSVFCG-LALYSRYHDCD-----PWTSKKVS 317

  Fly   303 ETSMILPMVLQYLTPDFVSFFGLGAVSA--AVMSSADSSVLSAASMFARNVYKLIFRQKASEMEI 365
            |...::|.::..:..::....||....|  ..:|:..||:.:.|::...::.|..|: ..||..:
  Rat   318 EVDQLMPYLVLDILKNYPGVPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPRFK-SLSEKSL 381

  Fly   366 IWVMRVAIIVVGILATIMALTIPSIYGLWSMCSDLVYVILFPQLL------MVVHFKKHCNTYGS 424
            .|:.:...::.|.|...|| .:.|:.|.....:..::.::...||      ::|.|   .|:.|:
  Rat   382 SWISQGMSVLYGALCIGMA-AVASLMGALLQAALSIFGMVGGPLLGLFSLGILVPF---ANSVGA 442

  Fly   425 LSAYIVALAIRLSGGEAILGLAPLIK---------------YPGYDEETKEQMFPFRTMAMLLSL 474
            .:..:...|:.|..|.......||.:               :.|.|..:..:| ||.|.|..:..
  Rat   443 FAGLLAGFAVSLWVGIGAQLYPPLPERTLPLSLETHGCNSTHNGTDWMSTTEM-PFSTSAFQIHD 506

  Fly   475 V--TLISVSWWTKMMFESGKLPPSYDYFRCV 503
            |  :.:..:|::.          ||.||..:
  Rat   507 VERSALMDNWYSL----------SYLYFSTI 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	110/527 (21%)
Slc5a8	NP_001178916.1	SLC5sbd_SMCT1	7..549	CDD:271402	115/551 (21%)