Protein Alignment ChT and slc5a1

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_956975.1
• Gene: slc5a1 / 393654
• ZFINID: ZDB-GENE-040426-1524
• Length: 658
• Species: Danio rerio
• Alignment Length: 699
• Identity: 161/699 - (23%)
• Similarity: 267/699 - (38%)
• Gaps: 194/699 - (27%)

  Fly     3 NIAGVVSIVLFYLLILVVGIWA----GRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGY 63
            |.|.:..||:::|::|.||:||    .|....|      ..|||||:..:....::.|:.:|.|:
Zfish    25 NPADISVIVIYFLVVLAVGVWAMVRTNRATVGG------FFLAGRSMVWWPIGASLFASNIGSGH 83

  Fly    64 I-----NGTAEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSF-GERMGG 122
            .     .|.|..|...|..|........|..:|..|:.     |.|.:||.:.|:..| |:|:..
Zfish    84 FVGIAGTGAAAGIAIGGFEWNALVVVIILGWLFVPIYI-----KAGVVTMPEYLKKRFGGQRIRI 143

  Fly   123 LLFLPALCGEVF-------WAAGIL--AALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSV 178
            .|.:.:||..||       :|..|.  .|||..:.:        :|::...|...||:.|||.:|
Zfish   144 YLSVLSLCLYVFTKISADMFAGAIFINQALGLNIYL--------AVVILLLITALYTVTGGLAAV 200

  Fly   179 AYTDVIQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVDW-------IG---------------HV- 220
            .|||.:|...:.:|.::.:.||::.  ||...:....:       ||               |:
Zfish   201 IYTDTLQTIIMVVGSFILMGFAFNK--VGGYENFRDSYMTAIPSVIGTNISESCYTPRADSFHIF 263

  Fly   221 -EP---KKHWLYIDYGLLLVFGGIPW-----QVYFQRVLSSKTAGRAQLLSYVAAAGCILMA--- 273
             :|   ...|..:.:||.:..|   |     ||..||.||:|.      ||:| .|||||..
Zfish   264 RDPINGDLPWPGLLFGLTIQAG---WYWCTDQVIVQRCLSAKN------LSHV-KAGCILCGYLK 318

  Fly   274 -IPPVLI---GAIAKATPWNETDYKGPYPLTVDE-----------TSMILPMVLQYLTPDFVSFF 323
             :|..|:   |.|::....:|.....|     ||           |::..|.::..|.|:.:...
Zfish   319 LLPMFLMVFPGMISRVLYPDEIACVDP-----DECKAVCGAEVGCTNIAYPKLVVDLMPNGLRGL 378

  Fly   324 GLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRV-AIIVVGI--------- 378
            .|..:.|::|||..|...||:::|..::|..| |.||.|.|::...|: .::::||
Zfish   379 MLSVMLASLMSSLTSIFNSASTLFTMDIYTKI-RPKAKEKELMIAGRLFMLLLIGISIAWIPIVQ 442

  Fly   379 -------------LATIMALTIPSIYGLWSMCSDLVYVILFPQLLMVVHFKKHCNTYGSLSAYIV 430
                         :.:.:|..|.:::.|...|                   |..|..|:.....|
Zfish   443 TAQSGQLFDYIQSITSYLAPPIAAVFALAIFC-------------------KRVNEPGAFYGLCV 488

  Fly   431 ALAIRLSGGEAILGLAPLIKYPGYDEETKEQMFP--------------FRTMAMLLSLVTLISVS 481
            .|         ::|||.:|....|.  |...:.|              |..:...||.:.::|:|
Zfish   489 GL---------LVGLARMITEFAYG--TGSCVNPSNCPTIICGVHYLYFALILFGLSCILILSIS 542

  Fly   482 WWTKMMFESGKLPPSYDYFRCVV---NIPEDVQ-RVGDPSESGEQLSVMAGPLARSYGAATMA-- 540
            ..||      .:...:.|..|..   |..|.:. ...|.:|..:..|:....:....|....|
Zfish   543 LMTK------PIEDKHLYRLCWSLRNNTEERIDLEADDWTEDQDSNSMETDEMREEPGCCKKAYN 601

  Fly   541 ---GKDERNGRINPALESDDDLPVAEARRINQETAQAQVKKMLDNATGV 586
               |.|:.|.   |.|..:.:   ||.:....:|.:..:.:.:.||..|
Zfish   602 WFCGFDQGNA---PKLTKEQE---AELKMKLTDTTEKPLWRNVVNANAV 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	136/579 (23%)
slc5a1	NP_956975.1	SLC5sbd_SGLT1	27..658	CDD:271379	160/697 (23%)