Protein Alignment ChT and Slc5a6

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_808538.1
• Gene: Slc5a6 / 330064
• MGIID: 2660847
• Length: 634
• Species: Mus musculus
• Alignment Length: 530
• Identity: 112/530 - (21%)
• Similarity: 200/530 - (37%)
• Gaps: 129/530 - (24%)

  Fly     2 INIAGVVSIVLFYLLI---LVVGI------WAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTAT 57
            |:...||..|:|.||:   ||:|:      |       |:.:..|:::|.|.:|......::.||
Mouse    20 ISTFSVVDYVVFGLLLVLSLVIGLYHACRGW-------GHHTVGELLMADRKMGCLPVALSLLAT 77

  Fly    58 WVGGGYINGTAEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGERMGG 122
            :.....|.|....|:..|..:......|.|.|:.....|.....:....:..:.|:..|.:.:
Mouse    78 FQSAVAILGAPAEIFRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKAV-- 140

  Fly   123 LLFLPALCGEVFWAAGILAALGA-------TLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAY 180
                 .:||.|.:...::..:|.       .|:.:...|...||:....:...||..|||.:|.:
Mouse   141 -----RICGTVTFIFQMVIYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKAVIW 200

  Fly   181 TDVIQLFCIFIGLWMCI----------PFAW--SNEHVGSLSDLEVD---WIGHVEPKKHWLYID 230
            |||.|...:|:|..:.|          ...|  :::| |.:|.:.:|   ::.|.    .|
Mouse   201 TDVFQTLVMFLGQLVVIIVGAARVGGLGHVWNVTSQH-GLISGINLDPDPFVRHT----FW---- 256

  Fly   231 YGLLLVFGGIPW--------QVYFQRVLSSKTAGRAQLLSYVAAAGCILMAI-PPVLIGAIAKAT 286
               .|.|||:..        |...||.|||.:. ||.:||..|...|..:|: ...|||.:..|
Mouse   257 ---TLAFGGVFMMLSLYGVNQAQVQRYLSSHSE-RAAVLSCYAVFPCQQVALCMSCLIGLVMFA- 316

  Fly   287 PWNETDYKGPYPLTVDETSMILPMVLQYLTPDFVSFF-GLGAVSAAVMSSADSSVLSAASMFARN 350
                  |...|.::.:........::.|...|.:... ||..:..|.:.|...|.:|:|
Mouse   317 ------YYNMYSMSPELKQAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSA------ 369

  Fly   351 VYKLIFRQKAS-EMEII---WVMRVAIIVVGILATIMALTIPSIYGLWSMCSDLVYVILFPQLLM 411
                 |...|: .||.:   |..:    :....|.:::..:...|||  :|..:.|:
Mouse   370 -----FNSLATVTMEDLIQPWFPQ----LTETRAIMLSRGLAFAYGL--VCLGMAYI-------- 415

  Fly   412 VVHFKKHCNTYGSLSAYIVALAIRLSG--GEAILGLAPLIKYPGYDEETKEQMFP-FRTMAMLLS 473
                ..|..:       ::..|:.:.|  |..:|||..|..:           || ...:..::.
Mouse   416 ----SSHLGS-------VLQAALSIFGMVGGPLLGLFCLGLF-----------FPCANPLGAIVG 458

  Fly   474 LVTLISVSWW 483
            |:|.:::::|
Mouse   459 LLTGLTMAFW 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	110/521 (21%)
Slc5a6	NP_808538.1	SLC5-6-like_sbd	23..548	CDD:444915	111/527 (21%)