Protein Alignment ChT and Slc5a4b

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_008771154.1
• Gene: Slc5a4b / 294342
• RGDID: 1309867
• Length: 660
• Species: Rattus norvegicus
• Alignment Length: 705
• Identity: 157/705 - (22%)
• Similarity: 259/705 - (36%)
• Gaps: 213/705 - (30%)

  Fly     3 NIAGVVSIVLFYLLILVVGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGT 67
            |.|.:..||:::|::|.||:|:..:...|...  ...||||.:..:....::.|:.:|..:..|.
  Rat    25 NAADISVIVIYFLVVLAVGLWSMVRSNRGTIG--GFFLAGRDVSWWPMGASLFASNIGSNHFVGL 87

  Fly    68 AEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGER-------MGGLLF 125
            |.....||:......:...|.::..|..|.....|.|..||.:.|:..||.:       :..|..
  Rat    88 AGTGAASGIAIAAVEWNALLMVLVLGWVFVPIYIKAGVTTMPEYLRKRFGGKRLQIYLSVLSLFI 152

  Fly   126 LPAL-------CGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDV 183
            :.|:       .|.:|    |..|||..|.:        :|.:...|..|||:.|||.||.|||.
  Rat   153 MVAIQTSSTIFSGAIF----IQLALGLNLYL--------AVFILLAITAFYTVAGGLASVIYTDS 205

  Fly   184 IQLFCIFIGLWMCIPFAWSNEHVGSLSDLEVDWIGHV------------------EPKKHWLYID 230
            :|.|.:.:|..:.:.||::  .||........::..:                  :|....::.|
  Rat   206 VQTFIMLVGSLILMGFAFA--EVGGYESFTEKYMNAIPSVVEGDNLTISPKCYTPQPDSFHIFRD 268

  Fly   231 YGLLLVFGGIPW------------------QVYFQRVLSSKTAGRAQLLSYVAAAGCI----LMA 273
                .:.|.|||                  ||..||.|..|.      :|:|.|| ||    |..
  Rat   269 ----PINGDIPWPGLIFGMTILAIWYWCADQVMVQRCLCGKN------MSHVKAA-CIMCGYLKL 322

  Fly   274 IPPVLI---GAIAKATPWNETDYKGPYPLTVDETSMILP--------------------MVLQYL 315
            :|..|:   |.|::.             |..|:.:.::|                    :||: |
  Rat   323 LPMFLMVMPGMISRI-------------LYTDKVACVVPSECVKQCGTAVGCTNYAYPTLVLE-L 373

  Fly   316 TPDFVSFFGLGAVSAAVMSSADSSVLSAASMFARNVYKLIFRQKASEMEIIWVMRVAIIVVGILA 380
            .||.:....|..:.|::|||..|...||:::|..::|..| |:||||.|::...||..||   |.
  Rat   374 MPDGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDLYTKI-RKKASERELMVAGRVFGIV---LI 434

  Fly   381 TIMALTIPSIYGLWSMCSDLV-YVILFPQ--------LLMVVHFKKHCNTYGSLSAYIVALAIRL 436
            .|..|.:|.|..  |....|. |:..|..        :.::..|.|..|..|:....:|.|
  Rat   435 VISILWVPLIQA--SQNGQLFHYISSFSSYIGPPVGAVFLLAIFCKRVNEQGAFWGLMVGL---- 493

  Fly   437 SGGEAILGLAPLIKYPGYDEETKEQMFP--------------FRTMAMLLSLVTLISVSWWTKMM 487
                 ::||..:|....|.  |...:.|              |..:...:|::.::.||:.|:.:
  Rat   494 -----VIGLIRMITEFIYG--TGSCLEPSNCPRIICGVHYMYFAIILFFVSILVILGVSFLTEPI 551

  Fly   488 FESGKLPPSYDYFRCVVNIPEDVQRVGDPSESGEQLSVMAGPLARSYGAATMAGKDERNGRINPA 552
                   |....:|...::..:.:         |::.:.|              :.|....:..|
  Rat   552 -------PDVHLYRLCWSLWNNTE---------ERIDLDA--------------EQETREEVGGA 586

  Fly   553 LESDDDLPVAEARR-------------------INQETAQAQVKKMLDNATGVKP 588
            ||.||    ||..|                   :.:|...|..:|..|  |..||
  Rat   587 LEEDD----AEQSRGCLRRACSLFCGLQSTGPKLTEEEEAALRQKFSD--TSEKP 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	132/573 (23%)
Slc5a4b	XP_008771154.1	SLC5-6-like_sbd	27..660	CDD:444915	156/703 (22%)