Protein Alignment ChT and Slc5a12

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001003915.1
• Gene: Slc5a12 / 241612
• MGIID: 2138890
• Length: 623
• Species: Mus musculus
• Alignment Length: 615
• Identity: 122/615 - (19%)
• Similarity: 230/615 - (37%)
• Gaps: 156/615 - (25%)

  Fly    11 VLFYLLILV---VGIWAGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATWVGGGYINGTAEAIY 72
            |:|..|.::   :|::...|::....| .|.::.||.:.......::||:::....:.||...:|
Mouse    12 VVFAGLFVISSGIGVFFAIKERKKTTS-REFLVGGRQMSFGPVALSLTASFMSAVTVLGTPAEVY 75

  Fly    73 TSGLVWCQAPFGYALSLVFGGIFFANPM-----RKQGYITMLDPLQDSFGERMGGLLFLPALCGE 132
            ..|..:    |.:.:|.|| .:||.:.:     .:.|..:..:.||..|.:.:.....:..:...
Mouse    76 RFGASF----FLFLISYVF-VVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYIVQT 135

  Fly   133 VFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLFGGLYSVAYTDVIQLFCIFIGLWMCI 197
            :.:...::.|....|:.:...:...||..:..:..||...|||.:|.:||..|:..:.:| ::.:
Mouse   136 ILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVG-FLTV 199

  Fly   198 PFAWSNEHVGSLSD-LE----------VDWIGHVEP-KKHWLYIDYGLLLVFGGIPW-------Q 243
            ....|| |||..:: ||          ||:  .|:| ::|    .:..:.:.|...|       |
Mouse   200 LIQGSN-HVGGFNNVLEKAGNGSRLHIVDF--DVDPLRRH----TFWTITIGGTFTWLGVYGVNQ 257

  Fly   244 VYFQRVLSSKTAGRAQLLSYVAAAGCILMAIPPVLIGAI-----AKATPWNETDYKGPYPLTVDE 303
            ...||.:|.||...|:|..|....|..::....|..|.|     ....||.......|
Mouse   258 STIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVISAP------- 315

  Fly   304 TSMILPMVLQYLTPDFVSFFGLGAVSAA-----VMSSADSSVLSAASMFARNVYKLIFRQKASEM 363
             ..::|..:..:   |.:..||..:..|     .:|:..:|:.:.|::...:..|..|...:.::
Mouse   316 -DQLMPYFVMEI---FATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDKL 376

  Fly   364 EIIWVMRVAIIVVGILATIMALTIPSIYG----------------------LWSMCSDLVYVILF 406
            . .|:.:...|:.||:.|.||: :.|:.|                      |.|:|    |.:..
Mouse   377 S-TWISKGLCILFGIMCTSMAV-VASLMGSVVQAPGIVSQERAITGSFQRNLASVC----YGVSI 435

  Fly   407 PQLLMVVHFKKHCNTYGSLSAYI--VALAIRLSGGEAILGLAPLIKYPGYDEETKEQMFPF---- 465
            .:|:|           |:|...:  :.|:..::.|..|        ||.  .|:|....|.
Mouse   436 WKLIM-----------GALGGLLTGITLSFWVAIGSFI--------YPA--PESKTLPLPLSTEH 479

  Fly   466 -------RTMAMLLSLVTLISVSWWTKMMFESGKLPPSYDYFRCVVNIPEDVQRVGDPSESGEQL 523
                   .|:|..:|...:::.:|::.          ||.||..|                 ..|
Mouse   480 CVELNITTTVAPQISSRPVLADTWYSL----------SYLYFSAV-----------------GCL 517

  Fly   524 SVMAGPLARSYGAATMAGKDERNGRINPAL 553
            ..:|..:..|:......|||     |:|.|
Mouse   518 GCIAAGIIISFLTGKQRGKD-----IDPLL 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	107/541 (20%)
Slc5a12	NP_001003915.1	SLC5-6-like_sbd	3..531	CDD:444915	116/597 (19%)