Protein Alignment ChT and LOC1274035

DIOPT Version :10

• Sequence 1: NP_650743.1
• Gene: ChT / 42245
• FlyBaseID: FBgn0038641
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: XP_313095.4
• Gene: LOC1274035 / 1274035
• VectorBaseID: AGAMI1_014717
• Length: 605
• Species: Anopheles gambiae
• Alignment Length: 711
• Identity: 133/711 - (18%)
• Similarity: 252/711 - (35%)
• Gaps: 211/711 - (29%)

  Fly     1 MINIAGVVSIVLFYLLILV---VGIW----AGRKKQSGNDSEEEVMLAGRSIGLFVGIFTMTATW 58
            |.:..||...|:|..::::   :|::    .|::|     :..|.:||.|::.::...|::.|::
Mosquito     1 MASAFGVWDYVVFIAMLMISAGIGVYYRFSGGKQK-----TNAEYLLADRNMSIWPVSFSLMASF 60

  Fly    59 VGGGYINGTAEAIYTSGLVWCQAPFGYALSLVFGGIFFANPMRKQGYITMLDPLQDSFGER---- 119
            :....:.|.:...|..|..:......|.|:.......|.....:....:..:.|:..||::
Mosquito    61 MSAITLLGVSNENYQFGTQFVAINLSYGLATPIAAYLFLPVFFRLQACSAYEYLEKRFGKKTRLA 125

  Fly   120 ------------MGGLLFLPALCGEVFWAAGILAALGATLSVIIDMDHRTSVILSSCIAIFYTLF 172
                        ||..::.|||                .|..:..:|...|::....|..||:..
Mosquito   126 ASLAYTLQMILYMGIAVYAPAL----------------ALQAVTGLDQAYSILAIGGICTFYSTI 174

  Fly   173 GGLYSVAYTDVIQLFCIFIGLWMCIPFA----------WSNEHVGSLSDLEVDWIGHVEPK---K 224
            ||:.:|.:|||.|...:|..::..|..|          |.....|  :.||: |  :.:|.   :
Mosquito   175 GGMKAVLFTDVFQSVLMFAAIYAVIICAAVKAGGLGPIWEAASEG--ARLEI-W--NFDPNPTTR 234

  Fly   225 H-WLYIDYGLLLVFGGI--PWQVYFQRVLSSKTAGRAQ-----------LLS----------YVA 265
            | |..:..|.:..:..:  ..|...||:.:.|....||           |||          |..
Mosquito   235 HTWWTLTIGGMFTYLSLYAVNQTQVQRLKTCKNLKSAQKALWLNWPILSLLSLSTSFSGLAIYYY 299

  Fly   266 AAGCILMAIPPVLIGAIA---KATPWNETDYKGPYPLTVDETSMILPMVLQYLTPDFVSFFGLGA 327
            ...|     .|:..|.|.   :..|....|..|..|        .||.:       |||  |:.:
Mosquito   300 YRSC-----DPLRQGRIKVRDQTMPLFVVDAMGDIP--------GLPGL-------FVS--GIFS 342

  Fly   328 VSAAVMSSADSSVLSAASM--FARNVYKLIFRQKASEMEIIWVMRVAIIVVGILATIMALTIPSI 390
            .|.:.:|:|.:| |:|.::  :.:.:|:.:.|:...:::..:..:|...:.|::...:|.....:
Mosquito   343 ASLSTVSAALNS-LAAVTLEDYLKPLYQKVKRKPMPDLQSSFPTKVMAFLYGVVCIAVAFLAQKM 406

  Fly   391 YGLWSMCSDLVYVI---LFPQLLMVVHFKKHCNTYGSLSAYIVALAIRLSGGEAILGLA---PLI 449
            .|:......:..|:   ||....|.: |....|..|.::..:|.|:..|     .:|..   |.:
Mosquito   407 GGVLQASLTIFGVVGGPLFALFTMGM-FTTRANQRGVITGLLVGLSFSL-----WIGFGQPRPPL 465

  Fly   450 KYPGYDEETKEQMFPFRTMAMLLSLVTLISVSWWTKMMFESGKLPPSYDYFRCVVNIPEDVQRVG 514
            |...:..|...:...:...::.|::                                   .||..
Mosquito   466 KTLDFSVEDCSEFGGYNQTSLPLAM-----------------------------------AQRAA 495

  Fly   515 DPSESGE-----QLSVM----AGPLAR---SYGAATMAG-----------KDERNGRINPALESD 556
            :|.:..:     :||.:    .|.|..   .||.:.:..           .||:...:|..|.|.
Mosquito   496 EPRDDSDYFYLYRLSYLWFSVLGYLVTFLVGYGTSVLLRWRGAQGTERIYLDEQQTYLNTDLFSP 560

  Fly   557 DDLPVAEARRINQETAQAQVKKMLDNATGVKPSGGGGGHL------QSQSGMAMP-TAEQD 610
               |||.|.:       .::.|.::|          ||.:      |..|.:.:| ||:||
Mosquito   561 ---PVARAMK-------QRLAKFIEN----------GGDIDATVRQQHSSRVDIPTTAKQD 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ChT	NP_650743.1	SLC5sbd_CHT	7..481	CDD:271368	102/544 (19%)
LOC1274035	XP_313095.4	SLC5sbd_NIS-SMVT	8..532	CDD:271383	110/613 (18%)