DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31224 and znf618

DIOPT Version :9

Sequence 1:	NP_001287396.1	Gene:	CG31224 / 42237	FlyBaseID:	FBgn0051224	Length:	1784	Species:	Drosophila melanogaster
Sequence 2:	NP_001313621.1	Gene:	znf618 / 100330008	ZFINID:	ZDB-GENE-030131-2063	Length:	827	Species:	Danio rerio

Alignment Length:	274	Identity:	58/274 - (21%)
Similarity:	84/274 - (30%)	Gaps:	106/274 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly  1466 CFTCGKKFYRWKNFSLHLKRH-------------LGWKEFGCYVCDKKFVVRSALVEHMRMHTGQ 1517
            |..||||:..:..|..|::.|             ||......|.||
Zfish    83 CGVCGKKYKYYNCFQTHVRAHSEAEGTVSGEGASLGINSAFRYTCD------------------- 128

  Fly  1518 TPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLK------ 1576
                  :||||:|.||...:||..|..    ...|    ..|:|          ..|||
Zfish   129 ------VCGKKYKYYSCFQEHRDLHAV----DDPY----DHVIP----------VEDLKEEAESF 169

  Fly  1577 ----PK----CCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHS 1633
                ||    .|.||..::.:.|..:.|:.|....|..:...:|..:..|....:.:..:.:.:|
Zfish   170 QKMGPKTGSYTCEYCGKQYKYFNPYQEHVALHAPLKGTFGLKLEGKLSGQSGQSSRVDINNSHNS 234

  Fly  1634 TE------------PQ--YDCAICSKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFK 1684
            ::            ||  |.|..|...|....||..|...||                   .|.:
Zfish   235 SDTPNSRTYTSLPSPQKTYTCGACGIQFQFYNNLLEHMQSHA-------------------ADNE 280

  Fly  1685 NHINAHKQIKPYTC 1698
            ||:   |:..|..|
Zfish   281 NHV---KEDSPKPC 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31224	NP_001287396.1	C2H2 Zn finger	1466..1486	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1494..1514	CDD:275368	3/19 (16%)
		zf-H2C2_2	1506..1531	CDD:290200	4/24 (17%)
		C2H2 Zn finger	1522..1542	CDD:275368	9/19 (47%)
		PHA00733	1527..1623	CDD:177301	25/109 (23%)
		C2H2 Zn finger	1554..1573	CDD:275370	2/18 (11%)
		C2H2 Zn finger	1580..1599	CDD:275368	5/18 (28%)
		C2H2 Zn finger	1613..1632	CDD:275368	1/18 (6%)
		COG5048	<1637..1780	CDD:227381	16/64 (25%)
		C2H2 Zn finger	1640..1660	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1670..1690	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1698..1718	CDD:275368	1/1 (100%)
		zf-H2C2_2	1710..1735	CDD:290200
		C2H2 Zn finger	1726..1746	CDD:275368
		zf-H2C2_2	1738..1763	CDD:290200
		C2H2 Zn finger	1754..1774	CDD:275368
znf618	NP_001313621.1	C2H2 Zn finger	83..103	CDD:275368	7/19 (37%)
		C2H2 Zn finger	127..147	CDD:275368	11/44 (25%)
		Dimer_Tnp_hAT	746..>788	CDD:283379
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24383
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.030