Protein Alignment CG7156 and KIF16B

DIOPT Version :10

• Sequence 1: NP_650697.1
• Gene: CG7156 / 42187
• FlyBaseID: FBgn0038588
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_005260807.1
• Gene: KIF16B / 55614
• HGNCID: 15869
• Length: 1883
• Species: Homo sapiens
• Alignment Length: 580
• Identity: 103/580 - (17%)
• Similarity: 193/580 - (33%)
• Gaps: 187/580 - (32%)

  Fly     7 GWIHSFTVTDT-----QEHKGGYTIYKITSIVFPRSVPQALTCLVV---------WKRFHDVKRL 57
            |.:.||:::.|     :|:.....:|  ...:||...|   .||.:         .::....::|
Human   567 GLLSSFSLSMTDLSKSRENLSAVMLY--NPGLFPIKGP---ICLRLEFERQQREELEKLESKRKL 626

  Fly    58 HRELSRRHKSLQLPGKLPVPTDSTYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQ 122
            ..|:..:.||           |....:|....|..:|||..:..|....|..:|.:
Human   627 IEEMEEKQKS-----------DKAELERMQQEVETQRKETEIVQLQIRKQEESLKR--------- 671

  Fly   123 ETPSPNGSPLKKLYVERSLRLQTEDNGCGSGGSETGTCAGAIADICDKLDLPYDPHDAGGITPLD 187
                      :..::|..|:                                            |
Human   672 ----------RSFHIENKLK--------------------------------------------D 682

  Fly   188 PRCDKEQTNNESQAKETEIELETKQEPKTDVALTKRDYLRLLTPMASIESDDSDYIYEAALEFSH 252
            ...:||:...|...::.||||:.|:: :.:..|..::.|:.|..:.:.|..:...|::...:...
Human   683 LLAEKEKFEEERLREQQEIELQKKRQ-EEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQK 746

  Fly   253 AVQ---AEVNLEYAEAHERYKHGV-----------------DLLLNGAKQDSSEERRFIAKAKIA 297
            ...   |::.||.....|:.|..|                 .||..|..|...||:|.:  ..|.
Human   747 EKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDL--EGIR 809

  Fly   298 KYLARAEEIHANFLANDCPTKKLQFQLSLDTTDGGSVSHLECPWNQLAR---YKVLQILQDRVMQ 359
            :.|.|.:|..|.                 ...||..:...:..:.:..|   .|::.:.:|.|.|
Human   810 ESLLRVKEARAG-----------------GDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQ 857

  Fly   360 VQCVTKS-QQPAAIMKGVE----------KPASHSLTQSIFLPQQVPYMVQLLAYFQSEQKIFLL 413
            ...:.|. |:...|::.::          :....|:|....:||.          |:..:.:...
Human   858 KDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQD----------FEKIKPVEYR 912

  Fly   414 LRQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKE-----AEEPPLTSDSDV----SDLV 469
            |:..|..:.| .||::.||..               |||:     .:..||:.|:.:    .::.
Human   913 LQYKERQLQY-LLQNHLPTLL---------------EEKQRAFEILDRGPLSLDNTLYQVEKEME 961

  Fly   470 RSSQQL--LKSVTNTLSNLQAGV-VTPKRNKKVDQNRIRSKPIPEQCLRQW--ACELAIA 524
            ...:||  .::..|.|..|||.. .|....::.::.|.:.|.|.|...:|.  |.|.|:|
Human   962 EKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALA 1021

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	23/129 (18%)
		MIT_SNX15	241..315	CDD:239140	19/93 (20%)
		Protein Kinases, catalytic domain	343..665	CDD:473864	43/210 (20%)
KIF16B	XP_005260807.1	KISc_KIF1A_KIF1B	2..365	CDD:276816
		Kinesin_assoc	364..476	CDD:465047
		FHA_KIF16B	446..562	CDD:438784
		Smc	<606..>1089	CDD:440809	92/536 (17%)