Protein Alignment CG7156 and nish-1

DIOPT Version :10

• Sequence 1: NP_650697.1
• Gene: CG7156 / 42187
• FlyBaseID: FBgn0038588
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_502016.2
• Gene: nish-1 / 177981
• WormBaseID: WBGene00008750
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 81/422 - (19%)
• Similarity: 136/422 - (32%)
• Gaps: 169/422 - (40%)

  Fly     1 MTLNLGGWIHSFTVTDTQEHKGGYTIYKITSIVFPRSVPQALTCLVVW---KRFHDVKR--LHRE 60
            |..|....|.:|.:.|    :|.||:|:|          |.......|   :|:.|...  :||.
 Worm    13 MDANFNAKILNFRMID----EGKYTVYRI----------QITVDTYTWTVERRYSDFDAYDVHRF 63

  Fly    61 LSRRHKSLQLPGKLPVPTDSTYFKRF---DAAVIQRRK----EYILQLLDFAAQHPALYKCSTFT 118
            |.|: ||. ||.|          ||.   |...|:.|:    :|:..||:...
 Worm    64 LDRK-KSF-LPPK----------KRLGNKDLEFIEERRLELEKYVRALLELEV------------ 104

  Fly   119 QFFQETPSPNGSPL-------------KKLYVERSLRLQTEDNGCGSGGSETGTCAGAIADICDK 170
             ::|:..:.:..||             ..:..:.||||    ...|.|..|:
 Worm   105 -WYQKQKNVHSLPLITAKFFDFHQYEIHSIVDDLSLRL----GNLGDGWLES------------- 151

  Fly   171 LDLPYDPHDAGGITPLDPRCDKEQTNNESQAKETEIELETKQEPKTDVALTKRDYLRLLTPMASI 235
                                  .|| :....:.|.|||.         |:|:|  |||..|.|
 Worm   152 ----------------------SQT-SPKYFEFTPIELH---------AITER--LRLPEPTA-- 180

  Fly   236 ESDDSDYIYEA--ALEFSHAVQA--------------------EVNLEYAEAHERYKHGVDLL-- 276
              .|.:.:.:.  .::|.|.|:|                    :::|.:.:       |:..|
 Worm   181 --PDVNMVADIGNTIDFLHRVRALKIRGQKGYVGTSNIVWNSLDMSLYFCK-------GLKALWI 236

  Fly   277 -------LNGAKQDSSEERRFI---AKAKIAKYLARAEEIHANFLANDCPTKKLQFQLSLDTTDG 331
                   :||.|......||.:   :..||...|...|::....|..:..|.|...::.|
 Worm   237 ADSDVCRINGIKSIRETLRRLVVHYSMKKIKDLLFDEEDLETGMLVEEMDTWKCLEEVDL----- 296

  Fly   332 GSVSHLEC---PWNQLARYKVLQILQDRVMQV 360
             |.:.::|   ....|...:||.:..:.:.::
 Worm   297 -SFNEIKCFDESMKLLPEVRVLNVSYNSITEI 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791	30/127 (24%)
		MIT_SNX15	241..315	CDD:239140	17/107 (16%)
		Protein Kinases, catalytic domain	343..665	CDD:473864	3/18 (17%)
nish-1	NP_502016.2	PX_domain	18..137	CDD:470617	32/157 (20%)
		LRR	<245..>420	CDD:443914	18/89 (20%)
		leucine-rich repeat	291..313	CDD:275380	4/27 (15%)
		leucine-rich repeat	314..336	CDD:275380	2/14 (14%)
		leucine-rich repeat	337..359	CDD:275380
		leucine-rich repeat	360..381	CDD:275380
		leucine-rich repeat	382..406	CDD:275380