Protein Alignment CG7156 and pkn2

DIOPT Version :10

• Sequence 1: NP_650697.1
• Gene: CG7156 / 42187
• FlyBaseID: FBgn0038588
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_004913783.1
• Gene: pkn2 / 100488854
• XenbaseID: XB-GENE-995298
• Length: 982
• Species: Xenopus tropicalis
• Alignment Length: 549
• Identity: 106/549 - (19%)
• Similarity: 187/549 - (34%)
• Gaps: 206/549 - (37%)

  Fly   175 YDPHDA--GGITPLDPRCDKEQTNNESQAKETEIELETKQEPKTDVALTKRDYLRLLTPMA---- 233
            |.|..|  ..:..:|||..:....:||...:.:.:||.:..|....:.:..|   |..|.|
 Frog   532 YSPQVAVPAAVPVVDPRNLELSPISESTVAKLDFDLEPEAPPAPPRSSSLGD---LYQPSAEHKA 593

  Fly   234 -SIESDDSDY---------IYEAALEFSHAVQAEV---NLEYAEAHERYKHGVDLLLNGAKQDSS 285
             ::...|::|         |.:...|.:  ::.|:   ::.|:...|                 |
 Frog   594 PNVPVPDTNYENSNNRISVIAKPTAEVT--IEPEIPVSDMNYSTIEE-----------------S 639

  Fly   286 EERRFIAKAKIAKYLARAEEIHANFLANDCPTKKLQFQLS-------LDTTDGGSVSHLEC-PWN 342
            |:||.                          .::.||.|.       |.....|.|...|. ..|
 Frog   640 EDRRI--------------------------QQRFQFSLQDFHCCAVLGRGHFGKVLLAEYKSTN 678

  Fly   343 QLARYKVLQ----ILQDRVMQVQCVTKSQQPAAIMKGVEKPASHSLTQSIFLPQQVPYMVQLLAY 403
            ::...|.|:    :.:|.|..:.|..:      |.:.|.. ..|            |::|.|.|.
 Frog   679 EMFAIKALKKGDIVARDEVDSLMCEKR------IFETVNS-VRH------------PFLVNLFAC 724

  Fly   404 FQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSDSDVSDL 468
            ||::..:..::..|.||.|..::.:...:..::|.|.
 Frog   725 FQTKDHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYA---------------------------- 761

  Fly   469 VRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQCLRQWACELAIAIHSLHGKGV 533
                                                             || :.:.:..||...:
 Frog   762 -------------------------------------------------AC-VVLGLQYLHEHKI 776

  Fly   534 ILRDLHMGNILLGAKGQLLLTYFYQNEGLTSDDNYVHKALNLEAVANHFVAPERPLTFRS----- 593
            :.|||.:.|:||..:|.:.:..|    ||..:........:.......|:||| .||..|
 Frog   777 VYRDLKLDNLLLDTEGFVKIADF----GLCKEGMGFGDRTSTFCGTPEFLAPE-VLTETSYTRAV 836

  Fly   594 DWWSYGVVLYQLLLG-VPYKVTHPG--QLDLYGC-----VQYPSESLEISDHAKDLLEQLLQLSP 650
            |||..||::|::|:| .|:    ||  :.:::..     |:||.   .:|..|..::.:||:.:|
 Frog   837 DWWGLGVLIYEMLVGESPF----PGDDEEEVFDSIVNDEVRYPR---FLSTEAISIMRRLLRRNP 894

  Fly   651 ELRL-----DYDQLQAHPFFKGIDWQAVL 674
            |.||     |.:.::.||||:..||.|:|
 Frog   895 ERRLGASEKDAEDVKKHPFFRHTDWNALL 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7156	NP_650697.1	PX_SNX15_like	8..124	CDD:132791
		MIT_SNX15	241..315	CDD:239140	10/85 (12%)
		Protein Kinases, catalytic domain	343..665	CDD:473864	66/343 (19%)
pkn2	XP_004913783.1	HR1_PKN_1	40..105	CDD:212012
		HR1	129..197	CDD:469609
		HR1	208..281	CDD:469609
		C2_PKN-like	390..471	CDD:176069
		STKc_PKN	655..980	CDD:270741	77/378 (20%)