Protein Alignment Non3 and RPF2

DIOPT Version :10

• Sequence 1: NP_650694.2
• Gene: Non3 / 42183
• FlyBaseID: FBgn0038585
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_115570.1
• Gene: RPF2 / 84154
• HGNCID: 20870
• Length: 306
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 142/303 - (46%)
• Similarity: 202/303 - (66%)
• Gaps: 2/303 - (0%)

  Fly     2 SLLRIRKPKTRKGKKVLLAREPQLIESARTMLFLDGRKCGGNVKLCMKDLQALKKPLVKVLNRKN 66
            :|.|:.||||::.|:.|..|||:|.|:.:..:.:.|......|...:||:.|||||...:..:||
Human     3 TLDRVVKPKTKRAKRFLEKREPKLNENIKNAMLIKGGNANATVTKVLKDVYALKKPYGVLYKKKN 67

  Fly    67 DITPFDDPSSLEFLTMKNDAALFTFGSTSKKRPDNIILGRIFENEVLDMFELGIKRYQAISEFKN 131
            ...||:|.:||||.:.|:|.:||.|||.:||||:|:::||:::..||||.||||:.:.::.:.||
Human    68 ITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIENFVSLKDIKN 132

  Fly   132 EKIGACVKPCLVFNGPKWAQTEELRRLRNLFIDTFQREKVDSIRLQGIEHVLSFTVTDDMNILMR 196
            .|.....||.|:|.|..:..||:.|||::|.||.|:...|.:|||.|:|:||.||..:. .|..|
Human   133 SKCPEGTKPMLIFAGDDFDVTEDYRRLKSLLIDFFRGPTVSNIRLAGLEYVLHFTALNG-KIYFR 196

  Fly   197 SYRILLKKSGQRTPRIELEEIGPSADFSIRRTKIASEDLYKQARKQPKQLKVGKKKNISTDALGN 261
            ||::||||||.|||||||||:|||.|..:|||.:||:||||.:.|.||.||..||||||.|..|.
Human   197 SYKLLLKKSGCRTPRIELEEMGPSLDLVLRRTHLASDDLYKLSMKMPKALKPKKKKNISHDTFGT 261

  Fly   262 TKGRVHLGKQQTGSIQTRRVKALRKTPEEK-KENRQRKKVALK 303
            |.||:|:.||....:|||::|.|:|.|.|: .|:.::|...:|
Human   262 TYGRIHMQKQDLSKLQTRKMKGLKKRPAERITEDHEKKSKRIK 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Non3	NP_650694.2	Brix	3..290	CDD:469999	138/286 (48%)
RPF2	NP_115570.1	Brix	6..297	CDD:469999	139/291 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..306		13/35 (37%)