DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Non3 and Rpf2

DIOPT Version :9

Sequence 1:	NP_650694.2	Gene:	Non3 / 42183	FlyBaseID:	FBgn0038585	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001099861.1	Gene:	Rpf2 / 294436	RGDID:	1306906	Length:	306	Species:	Rattus norvegicus

Alignment Length:	298	Identity:	138/298 - (46%)
Similarity:	197/298 - (66%)	Gaps:	1/298 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLLRIRKPKTRKGKKVLLAREPQLIESARTMLFLDGRKCGGNVKLCMKDLQALKKPLVKVLNRKN 66
            :|.::.||||::.|:.|..|||:|.|:.:..:.:.|......|...::|:.|||||...:..:||
  Rat     3 ALDKVLKPKTKRAKRFLEKREPKLSENIKNAMLIKGGNANATVTQVLRDVYALKKPYGVLYKKKN 67

  Fly    67 DITPFDDPSSLEFLTMKNDAALFTFGSTSKKRPDNIILGRIFENEVLDMFELGIKRYQAISEFKN 131
            ...||:|.:||||.:.|:|.:||.|||.:||||:|:::||:::..||||.||||:::.::.:.|.
  Rat    68 ITRPFEDQTSLEFFSKKSDCSLFMFGSHNKKRPNNLVIGRMYDYHVLDMIELGIEKFVSLKDIKT 132

  Fly   132 EKIGACVKPCLVFNGPKWAQTEELRRLRNLFIDTFQREKVDSIRLQGIEHVLSFTVTDDMNILMR 196
            .|.....||.|:|.|..:..||:.|||:||.||.|:...|.::||.|:|:||.||..:. .:..|
  Rat   133 SKCPEGTKPMLIFAGDDFDVTEDYRRLKNLLIDFFRGPTVSNVRLAGLEYVLHFTALNG-KVYFR 196

  Fly   197 SYRILLKKSGQRTPRIELEEIGPSADFSIRRTKIASEDLYKQARKQPKQLKVGKKKNISTDALGN 261
            ||::||||||.|||||||||:|||.|..:|||.:||:||||.:.|.||.||..|:||||.|..|.
  Rat   197 SYKLLLKKSGCRTPRIELEEMGPSLDLVVRRTHLASDDLYKLSMKVPKALKPKKRKNISQDTFGT 261

  Fly   262 TKGRVHLGKQQTGSIQTRRVKALRKTPEEKKENRQRKK 299
            |.||:|:.||....:|||:||.|:|.|.|.....|.||
  Rat   262 TFGRIHMQKQDLSKLQTRKVKGLKKRPAENGVEDQGKK 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Non3	NP_650694.2	Brix	3..290	CDD:412658	134/286 (47%)
Rpf2	NP_001099861.1	Brix	6..286	CDD:294606	131/280 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341753
Domainoid	1	1.000	177	1.000	Domainoid score	I3503
eggNOG	1	0.900	-	-		E1_COG5106
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6404
Inparanoid	1	1.050	273	1.000	Inparanoid score	I2907
OMA	1	1.010	-	-		QHG53948
OrthoDB	1	1.010	-	-		D434863at33208
OrthoFinder	1	1.000	-	-		FOG0005406
OrthoInspector	1	1.000	-	-		oto98869
orthoMCL	1	0.900	-	-		OOG6_102220
Panther	1	1.100	-	-	LDO	PTHR12728
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3835
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770