Protein Alignment Alg1 and ALG2

DIOPT Version :10

• Sequence 1: NP_650662.1
• Gene: Alg1 / 42146
• FlyBaseID: FBgn0038552
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_149078.1
• Gene: ALG2 / 85365
• HGNCID: 23159
• Length: 416
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 43/223 - (19%)
• Similarity: 80/223 - (35%)
• Gaps: 72/223 - (32%)

  Fly   224 AKDAEQSDVLEATALTQKLASGVVQYRPQRQAVLVSSTSWTPDEDFGILLKALQAYEETAQAEPL 288
            ::|.|:..::.|....:::...|..|:..::.|..|        |.|..:..|:::.:..:...|
Human   256 SQDWERVHLIVAGGYDERVLENVEHYQELKKMVQQS--------DLGQYVTFLRSFSDKQKISLL 312

  Fly   289 VYPSLLCIITGKGPQKEHY-VAEIEKLQWQKVSVITPWLEIEDYPTVLASADLGVCLHWSTSGLD 352
              .|..|::  ..|..||: :..:|.:..|                         |
Human   313 --HSCTCVL--YTPSNEHFGIVPLEAMYMQ-------------------------C--------- 339

  Fly   353 LPMKVVDMFGSGLPVCAYDFKCLDELVKHGENGFVF-GDHVQLAEQLRIWFENFPKNPSILET-- 414
             |:..|:   ||.|:         |.:.|...||:. .|.|..:|.:    |.|.:.||:..|
Human   340 -PVIAVN---SGGPL---------ESIDHSVTGFLCEPDPVHFSEAI----EKFIREPSLKATMG 387

  Fly   415 ---RAGFQRKI--QEFQELRWRESWRLI 437
               ||..:.|.  :.|.|..:|...:|:
Human   388 LAGRARVKEKFSPEAFTEQLYRYVTKLL 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alg1	NP_650662.1	GT33_ALG1-like	6..442	CDD:340843	43/223 (19%)
ALG2	NP_149078.1	GT4_ALG2-like	17..407	CDD:340834	41/213 (19%)